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心内科门诊中阻塞性睡眠呼吸暂停的潜在漏诊。

Potential underdiagnosis of obstructive sleep apnoea in the cardiology outpatient setting.

机构信息

Hypertension Unit, Cardiology Division, Heart Institute (InCor), Faculty of Medicine, University of São Paulo, Sao Paulo, Brazil.

Sleep Laboratory, Pulmonary Division, Heart Institute (InCor), Faculty of Medicine, University of São Paulo, Sao Paulo, Brazil.

出版信息

Heart. 2015 Aug;101(16):1288-92. doi: 10.1136/heartjnl-2014-307276. Epub 2015 Apr 20.

Abstract

INTRODUCTION

Consistent evidence suggests that obstructive sleep apnoea (OSA) is associated with increased cardiovascular risk. However, it is unclear whether OSA is underdiagnosed in the cardiology outpatient setting. In the present study, we prospectively evaluated the potential underdiagnosis of OSA in several subspecialties from a tertiary cardiology university hospital.

METHODS

Consecutive outpatients from five subspecialties (hypertension, coronary, arrhythmia, heart failure (HF), valvular heart disease) were studied. We performed anthropometric measurements, assessed the risk of OSA using the Berlin Questionnaire and evaluated the prior diagnosis and treatment for OSA. In a subset of patients randomly selected, we performed portable sleep monitoring to objectively evaluate the presence of OSA (defined by an apnoea-hypopnoea index ≥15 events/h of sleep).

RESULTS

We evaluated 500 patients (100 from each subspecialty). The mean age and body mass index (BMI) were 59±13 years and 28.2±5.3 kg/m(2), respectively. We found that 51.6% (258 patients) had a high risk for OSA (Berlin Questionnaire). However, only 13 (3.1%) of these patients had a previous diagnosis of OSA. Of those, only six patients were receiving specific OSA treatment. Fifty patients (10 from each specialty) participated in sleep studies. No differences were found in patients who underwent sleep monitoring and those who did not. We found a high frequency of OSA (66%), varying from 50% (hypertension group) to 80% (HF group).

CONCLUSIONS

Despite significant scientific evidence pointing to OSA as an emerging cardiovascular risk factor, OSA is still underdiagnosed in several cardiology subspecialties.

摘要

简介

一致的证据表明,阻塞性睡眠呼吸暂停(OSA)与心血管风险增加有关。然而,在心脏病学门诊环境中,OSA 是否存在诊断不足尚不清楚。在本研究中,我们前瞻性地评估了来自一家三级心脏病大学医院的五个专科(高血压、冠心病、心律失常、心力衰竭(HF)、瓣膜性心脏病)中 OSA 的潜在诊断不足。

方法

连续评估了五个专科(高血压、冠心病、心律失常、心力衰竭(HF)、瓣膜性心脏病)的门诊患者。我们进行了人体测量学测量,使用柏林问卷评估 OSA 的风险,并评估了 OSA 的先前诊断和治疗。在随机选择的患者亚组中,我们进行了便携式睡眠监测以客观评估 OSA 的存在(定义为睡眠时每小时呼吸暂停-低通气指数≥15 次)。

结果

我们评估了 500 名患者(每个专科 100 名)。平均年龄和体重指数(BMI)分别为 59±13 岁和 28.2±5.3kg/m2。我们发现,51.6%(258 名患者)有 OSA 的高风险(柏林问卷)。然而,只有 13 名(3.1%)患者有 OSA 的先前诊断。其中,只有 6 名患者接受了特定的 OSA 治疗。50 名患者(每个专科 10 名)参加了睡眠研究。接受睡眠监测和未接受睡眠监测的患者之间没有差异。我们发现 OSA 的发生率很高(66%),从 50%(高血压组)到 80%(HF 组)不等。

结论

尽管有大量科学证据表明 OSA 是一种新兴的心血管危险因素,但在几个心脏病学专科中,OSA 的诊断仍然不足。

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