Parungao Jose Mari, Hanouneh Ibrahim A, John Binu, Alkhouri Naim, Zein Nizar N
Department of Gastroenterology, Providence Hospital and Medical Centers, Southfield, MI, USA.
Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic.
Cleve Clin J Med. 2015 Feb;82(2):97-104. doi: 10.3949/ccjm.82a.14004.
The interleukin-28B (IL28B) gene contains a single-nucleotide polymorphism at location rs12979860 that affects both the natural history of hepatitis C virus infection and the patient's response to treatment, particularly interferon-based regimens with or without protease inhibitors.