Wang Ya-jie, Li Qi, Li Yu-jie, Yang Qing, Chen Ying, Weng Xiao-gang, Kan Xiao-xi, Chen Xi, Zhu Xiao-xinr
Zhongguo Zhong Yao Za Zhi. 2014 Dec;39(24):4693-8.
Multi-drug resistance (MDR) is one of the major obstacles to successful chemotherapy for tumors. Traditional Chinese medicine that can reverse MDR has been intensely studied because of its low toxicity, high efficacy and multi-targets. In recent years, more and more traditional Chinese medicine (TCM) has been found to be effective in reversing MDR. In this review, we analyze the current status of traditional Chinese medicine on reversing tumor MDR and describe recent progress on it.
多药耐药(MDR)是肿瘤化疗成功的主要障碍之一。由于其低毒性、高效性和多靶点,能够逆转多药耐药的传统中药受到了广泛研究。近年来,越来越多的传统中药被发现具有逆转多药耐药的作用。在这篇综述中,我们分析了传统中药在逆转肿瘤多药耐药方面的现状,并描述了其最新进展。