Mereish Ethan H, Lee Ji Hyun, Gamarel Kristi E, Zaller Nickolas D, Operario Don
Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, School of Public Health, Brown University, Box G-S121-4, Providence RI 02912, USA.
Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, School of Public Health, Brown University, Box G-S121-4, Providence RI 02912, USA.
Addict Behav. 2015 Aug;47:80-5. doi: 10.1016/j.addbeh.2015.03.023. Epub 2015 Mar 31.
Sexual minority women (SMW) are at greater risk for alcohol use disorders (AUDs) compared to heterosexual women. However, there is a dearth of research on sexual orientation disparities in co-occurring disorders among women with AUDs. We examined disparities in lifetime co-occurring psychiatric and drug use disorders among a nationally representative sample of women with lifetime AUDs.
Data were analyzed from the 2004-2005 (Wave 2) of the National Epidemiological Survey on Alcohol and Related Conditions (NESARC), which was collected in structured diagnostic face-to-face interviews. Adult women with AUDs (N=4342) were included in the analyses and approximately 191 of those women self-identified as SMW. Lifetime alcohol and drug use disorders and psychiatric disorders were assessed using DSM-IV criteria. We conducted multivariate logistic regression analyses to compare SMW and heterosexual women with lifetime AUDs on lifetime psychiatric disorders and drug use disorders, while adjusting for sociodemographic variables.
While accounting for several covariates, SMW with lifetime AUDs were more likely than heterosexual women with lifetime AUDs to have lifetime psychiatric disorders (e.g., mood, anxiety, panic disorders) and drug use disorders (e.g., prescription drugs, cannabis use disorders).
Sexual minority women with lifetime alcohol use disorders are at heightened risk for co-occurring psychiatric and drug use disorders than heterosexual women with lifetime alcohol use disorders. The findings warrant the need for more research and empirically based interventions for the comprehensive treatment and prevention of alcohol use disorders among sexual minority women.
与异性恋女性相比，性少数群体女性（SMW）患酒精使用障碍（AUDs）的风险更高。然而，对于患有酒精使用障碍的女性共病中的性取向差异，研究匮乏。我们在全国代表性的患有酒精使用障碍的女性样本中，研究了终生共病的精神疾病和药物使用障碍中的差异。
对2004 - 2005年（第2波）全国酒精及相关状况流行病学调查（NESARC）的数据进行分析，该调查通过结构化诊断面对面访谈收集。分析纳入患有酒精使用障碍的成年女性（N = 4342），其中约191名女性自我认定为性少数群体女性。使用《精神疾病诊断与统计手册》第四版（DSM-IV）标准评估终生酒精和药物使用障碍以及精神疾病。我们进行多变量逻辑回归分析，以比较患有终生酒精使用障碍的性少数群体女性和异性恋女性在终生精神疾病和药物使用障碍方面的情况，同时对社会人口统计学变量进行调整。
在考虑多个协变量的情况下，患有终生酒精使用障碍的性少数群体女性比患有终生酒精使用障碍的异性恋女性更有可能患有终生精神疾病（如情绪、焦虑、惊恐障碍）和药物使用障碍（如处方药、大麻使用障碍）。
患有终生酒精使用障碍的性少数群体女性比患有终生酒精使用障碍的异性恋女性患共病精神疾病和药物使用障碍的风险更高。这些发现表明需要进行更多研究，并采取基于实证的干预措施，以全面治疗和预防性少数群体女性的酒精使用障碍。
