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Chiari-1畸形的后颅窝减压术及硬脑膜成形术

Posterior fossa decompression with duraplasty in Chiari-1 malformations.

作者信息

Rehman Lal, Akbar Hamid, Bokhari Iram, Babar Asghar Khan, M Hashim A Sattar, Arain Safdar Hussain

机构信息

Department of Neurosurgery, Jinnah Postgraduate Medical Centre, Karachi.

出版信息

J Coll Physicians Surg Pak. 2015 Apr;25(4):254-8.

Abstract

OBJECTIVE

To evaluate the symptomatic outcome after PFD (Posterior Fossa Decompression) with duraplasty in Chiari-1 malformations.

STUDY DESIGN

Case series.

PLACE AND DURATION OF STUDY

Department of Neurosurgery, JPMC, Karachi, from July 2008 to September 2012.

METHODOLOGY

This included 21 patients of Chiari 1 malformations admitted in department through OPD with clinical features of headache, neck pain, numbness, neurological deficit, and syringomyelia. Diagnosis was confirmed by MRI. PFD followed by C1 laminectomy with duraplasty was done in all cases and symptomatic outcome was assessed in follow-up clinic.

RESULTS

Among 21 patients, 13 were females and 8 were males. Age ranged from 18 to 40 years. All the patients had neck pain and numbness in hands. Only 3 patients had weakness of all four limbs and 12 with weakness of hands. Symptoms evolved over a mean of 12 months. Syringomyelia was present in all cases. All patients underwent posterior fossa decompression with duraplasty with an additional C1 laminectomy and in 2 cases C2 laminectomy was done. Syringo-subarachnoid shunt was placed in one patient and ventriculo-peritoneal shunt was placed in 2 patients. Pain was relieved in all cases. Weakness was improved in all cases and numbness was improved in 19 cases. Syringomyelia was improved in all cases. Postoperative complications included CSF leak in 2 patients and wound infection in one patient. However, there was no mortality.

CONCLUSION

Posterior fossa decompression with duraplasty is the best treatment option for Chiari-1 malformations because of symptomatic improvement and less chances of complications.

摘要

目的

评估 Chiari-1 畸形行后颅窝减压术并硬脑膜成形术后的症状改善情况。

研究设计

病例系列研究。

研究地点及时间

2008 年 7 月至 2012 年 9 月,卡拉奇 JPMC 神经外科。

方法

本研究纳入 21 例 Chiari 1 畸形患者,这些患者通过门诊收入科室,具有头痛、颈部疼痛、麻木、神经功能缺损和脊髓空洞症等临床特征。通过磁共振成像(MRI)确诊。所有病例均行后颅窝减压术,随后行 C1 椎板切除术并硬脑膜成形术,并在随访门诊评估症状改善情况。

结果

21 例患者中,女性 13 例,男性 8 例。年龄在 18 至 40 岁之间。所有患者均有颈部疼痛和手部麻木。仅 3 例患者四肢无力,12 例患者手部无力。症状平均持续 12 个月。所有病例均存在脊髓空洞症。所有患者均接受后颅窝减压术并硬脑膜成形术,另外行 C1 椎板切除术,2 例患者行 C2 椎板切除术。1 例患者行脊髓空洞 - 蛛网膜下腔分流术,2 例患者行脑室 - 腹腔分流术。所有病例疼痛均缓解。所有病例无力症状均改善,19 例患者麻木症状改善。所有病例脊髓空洞症均改善。术后并发症包括 2 例患者脑脊液漏和 1 例患者伤口感染。然而,无死亡病例。

结论

后颅窝减压术并硬脑膜成形术是 Chiari-1 畸形的最佳治疗选择,因为其能改善症状且并发症发生几率较低。

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