Sahai Puja, Shukla Nootan Kumar, Arora Saurabh, Mohanti Bidhu Kalyan
Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, India.
Department of Surgical Oncology, All India Institute of Medical Sciences, New Delhi, India.
Head Neck. 2016 Jan;38(1):E16-9. doi: 10.1002/hed.24089. Epub 2015 Jul 18.
The purpose of this study was for us to describe a case of recurrent sebaceous carcinoma treated with postoperative reirradiation.
A 38-year-old man was diagnosed with sebaceous carcinoma of the right lower eyelid. The patient developed local recurrence 4 times, with the first one at 30 months after the excision. The first local recurrence was treated with excision and postoperative radiotherapy with 60 Gy/30 fractions/6 weeks. He manifested preauricular nodal metastasis with the third local recurrence, which was confirmed with (18)F-fluorodeoxyglucose positron emission tomography-CT ((18)F-FDG PET-CT). He received 2 courses of adjuvant reirradiation to the right orbit with 45 Gy/25 fractions/5 weeks and 30 Gy/15 fractions/3 weeks, respectively.
The patient was successfully treated with no evidence of locoregional recurrence at 2 years after the cancer-directed therapy. The patient's follow-up from the date of diagnosis has been 9 years.
Adjuvant reirradiation with modest doses may be considered with a view to provide disease control and long-term survival.
本研究的目的是描述一例复发性皮脂腺癌患者接受术后再程放疗的病例。
一名38岁男性被诊断为右下睑皮脂腺癌。患者局部复发4次，首次复发于切除术后30个月。首次局部复发采用切除及术后放疗，剂量为60 Gy/30次/6周。第三次局部复发时出现耳前淋巴结转移，经（18）F-氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描（（18）F-FDG PET-CT）证实。他分别接受了2个疗程的右眼眶辅助再程放疗，剂量分别为45 Gy/25次/5周和30 Gy/15次/3周。
患者经癌症导向治疗2年后成功治愈，无局部区域复发迹象。自诊断之日起，患者的随访时间已达9年。
为实现疾病控制和长期生存，可考虑采用适度剂量的辅助再程放疗。
