Chudgar Neel P, Bucciarelli Peter R, Jeffries Elizabeth M, Rizk Nabil P, Park Bernard J, Adusumilli Prasad S, Jones David R
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Thorac Surg Clin. 2015 May;25(2):145-53. doi: 10.1016/j.thorsurg.2014.11.002. Epub 2015 Feb 2.
The National Lung Screening Trial was a large, multicenter, randomized controlled trial published in 2011. It found that annual screening with low-dose CT (LDCT) in a high-risk population was associated with a 20% reduction in lung cancer-specific mortality compared with conventional chest radiography. Several leading professional organizations have since put forth lung cancer screening guidelines that include the use of LDCT, largely on the basis of this study. Broad adoption of these screening recommendations, however, remains a challenge.
国家肺癌筛查试验是一项大型、多中心、随机对照试验，于2011年发表。该试验发现，与传统胸部X光检查相比，在高危人群中每年进行低剂量CT（LDCT）筛查可使肺癌特异性死亡率降低20%。此后，几个主要的专业组织提出了肺癌筛查指南，其中包括使用LDCT，这主要是基于这项研究。然而，广泛采用这些筛查建议仍然是一项挑战。
