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经阴道网片手术的围手术期结局及前瞻性患者报告结局指标

Perioperative outcomes and prospective patient reported outcome measures for transvaginal mesh surgery.

作者信息

Balchandra Pooja, Marsh Fiona, Landon Christine

机构信息

Department of Urogynaecology, St James's University Hospital, Level 1, Chancellor Wing, Beckett Street, Leeds, LS97TF, UK,

出版信息

Arch Gynecol Obstet. 2015 Oct;292(4):875-82. doi: 10.1007/s00404-015-3724-z. Epub 2015 Apr 24.

Abstract

PURPOSE

To determine perioperative morbidity associated with the transvaginal mesh and analyse patient reported outcome measures following transvaginal mesh surgery via a prospective cohort study.

METHODS

A retrospective review and a prospective cohort study of vaginal symptoms via a validated questionnaire (Ethically approved). 159 consecutive women who underwent transvaginal polypropylene mesh repair for pelvic organ prolapse from January 2009 to January 2012 by a single experienced urogynaecologist were identified using theatre records and formed the study population. The type and frequency of intraoperative and postoperative complications, mesh exposure rates and need for further surgery were recorded. 59/159 patients consented to complete both preoperative and postoperative assessment of vaginal symptoms using the validated International Consultation on Incontinence Modular Questionnaire-Vaginal symptoms (ICIQ-VS). 51/59 patients completed both questionnaires.

RESULTS

The average age of the study population was 63 years (range 39-87 years). The mean BMI was 28.5 (range 20-40). 86 % (n = 138/159) had a previous hysterectomy. 98 % (n = 156/159) of patients did not have any intraoperative complications. 0.62 % (n = 1/159) had a bladder injury. Mesh exposure was noted in 4 % of the entire group (n = 6/135) at follow-up with overall reoperation rate of 9 % (n = 13/135). Statistically significant improvement in most arms of the ICIQ-VS questionnaire was noted in the cohort of 51 patients at follow-up.

CONCLUSION

Our data revealed a very low intraoperative complication rate with a mesh exposure rate of 4 %. The prospective study showed a statistically significant improvement in vaginal symptoms.

摘要

目的

通过一项前瞻性队列研究,确定经阴道网片相关的围手术期发病率,并分析经阴道网片手术后患者报告的结局指标。

方法

通过一份经过验证的问卷(经伦理批准)对阴道症状进行回顾性分析和前瞻性队列研究。利用手术记录确定了2009年1月至2012年1月期间由一位经验丰富的泌尿妇科医生为盆腔器官脱垂进行经阴道聚丙烯网片修补术的159名连续女性,她们构成了研究人群。记录术中及术后并发症的类型和发生率、网片暴露率以及再次手术的需求。159名患者中有59名同意使用经过验证的《国际尿失禁咨询委员会模块化问卷 - 阴道症状》(ICIQ - VS)完成术前和术后阴道症状评估。59名患者中有51名完成了两份问卷。

结果

研究人群的平均年龄为63岁(范围39 - 87岁)。平均体重指数为28.5(范围20 - 40)。86%(n = 138/159)曾行子宫切除术。98%(n = 156/159)的患者术中无任何并发症。0.62%(n = 1/159)发生膀胱损伤。随访时,整个组中有4%(n = 6/135)出现网片暴露,总体再次手术率为9%(n = 13/135)。在随访的51名患者队列中,ICIQ - VS问卷的大多数项目显示出统计学上的显著改善。

结论

我们的数据显示术中并发症发生率极低,网片暴露率为4%。前瞻性研究表明阴道症状有统计学上的显著改善。

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