Mendez Melissa H, Joh Daniel Y, Gupta Rajan, Polascik Thomas J
Duke Cancer Institute, Duke University Medical Center, DUMC, Box 2804, Durham, NC, 27710, USA,
Curr Urol Rep. 2015 Jun;16(6):35. doi: 10.1007/s11934-015-0513-y.
Prostate cancer (PCa) care is an ever-evolving field. Research and technological developments continue to refine our definitions and management of this disease. Now, with a greater understanding of the natural history of PCa, the prevention of overtreatment has shaped a new era with the adoption of active surveillance (AS) and advancement of focal therapy (FT). Multiparametric magnetic resonance imaging (mpMRI) allows us to define, locate, and monitor cancers in a way never before possible. These capabilities combined with promising results from current prospective studies have changed the face of FT. This review presents the latest developments, current trends, and next steps in FT.
前列腺癌（PCa）护理是一个不断发展的领域。研究和技术发展持续完善我们对这种疾病的定义和管理。如今，随着对PCa自然史有了更深入的了解，避免过度治疗推动了一个新时代的到来，即采用主动监测（AS）和聚焦治疗（FT）的进展。多参数磁共振成像（mpMRI）使我们能够以前所未有的方式定义、定位和监测癌症。这些能力与当前前瞻性研究的喜人结果相结合，改变了FT的面貌。本综述介绍了FT的最新进展、当前趋势和下一步计划。
