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2013/2014流行季节波兰针对流感病毒血凝素的循环抗体发生率

Incidence of Circulating Antibodies Against Hemagglutinin of Influenza Viruses in the Epidemic Season 2013/2014 in Poland.

作者信息

Bednarska K, Nowak M A, Kondratiuk K, Hallmann-Szelińska E, Brydak L B

机构信息

Department of Influenza Research, National Influenza Centre, National Institute of Public Health - National Institute of Hygiene, 24 Chocimska St., 00-791, Warsaw, Poland.

出版信息

Adv Exp Med Biol. 2015;857:45-50. doi: 10.1007/5584_2015_118.

Abstract

The aim of this study was to determine the level of antibodies against hemagglutinin of influenza viruses in the sera of people in different age groups in the epidemic season 2013/2014 in Poland. The level of anti-hemagglutinin antibodies was determined by hemagglutination inhibition test (HAI). A total number of 1,050 randomly selected sera was tested in seven age groups. The level of antibodies against influenza viruses was very low, which indicates that the people have not been vaccinated against influenza in the epidemic season 2013/2014. The value of protection rate against influenza in the Polish population is very low. These results are worrying, because complications of influenza may be harmful to health and even life-threatening to persons who are not vaccinated. Furthermore, these results confirm the circulation of three antigenically different influenza virus strains, two subtypes of influenza A virus--A/California/7/2009/(H1N1)pdm09 and A/Victoria/361/2011(H3N2)--and B/Massachusetts/2/2012.

摘要

本研究的目的是测定2013/2014年流行季节波兰不同年龄组人群血清中流感病毒血凝素抗体水平。通过血凝抑制试验(HAI)测定抗血凝素抗体水平。在七个年龄组中对总共1050份随机选取的血清进行了检测。流感病毒抗体水平非常低,这表明在2013/2014年流行季节人们未接种流感疫苗。波兰人群中流感的保护率非常低。这些结果令人担忧,因为流感并发症可能对健康有害,甚至对未接种疫苗的人有生命危险。此外,这些结果证实了三种抗原性不同的流感病毒株的传播,即两种甲型流感病毒亚型——A/加利福尼亚/7/2009/(H1N1)pdm09和A/维多利亚/361/2011(H3N2)——以及B/马萨诸塞/2/2012。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d710/7119922/0887aa93e90b/336332_1_En_118_Fig1_HTML.jpg

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