Keshvani N, Feurer I D, Rumbaugh E, Dreher A, Zavala E, Stanley M, Schaefer H M
Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Department of Surgery, Vanderbilt University Medical Center, Nashville, TN.
Am J Transplant. 2015 Aug;15(8):2126-35. doi: 10.1111/ajt.13265. Epub 2015 Apr 22.
With the changing demographics of the living donor population and increased regulatory oversight, it is important that transplant centers report outcomes accurately. The aim of our retrospective cohort study of 312 living donors who underwent nephrectomy between 2008 and 2013 was to evaluate the impact of living donor program performance improvement initiatives on: (i) transplant center program reporting compliance; (ii) patient compliance with postdonation follow-up and its associated factors; and (iii) overall financial costs to the transplant center. The effect of the initiatives (donation eras 2008-2010 and 2011-2013) on compliance at key reporting points (6 months, 1 year, 2 years) was analyzed using correlation coefficients, χ(2) and Fisher's exact tests. Multivariable logistic regression models tested the initiatives' effect on the likelihood of patient follow-up. The initiatives were associated with significant improvement in form reporting compliance (r ≥ 0.862, p ≤ 0.027; 1 and 2 year Fisher's Exact p ≤ 0.002) and patient follow-up (χ(2) p ≤ 0.009) with acceptable transplant center costs. Multivariable analyses demonstrated that donation era was consistently and significantly (p < 0.001) associated with increased likelihood of postdonation patient follow-up. Institution of performance improvement initiatives with dedicated program resources is financially feasible and leads to more accurate and complete form reporting and improved patient follow-up after nephrectomy.
随着活体供者人群人口统计学特征的变化以及监管监督的加强,移植中心准确报告结果非常重要。我们对2008年至2013年间接受肾切除术的312名活体供者进行回顾性队列研究的目的是评估活体供者项目绩效改进举措对以下方面的影响:(i)移植中心项目报告的合规性;(ii)患者对捐献后随访的依从性及其相关因素;(iii)移植中心的总体财务成本。使用相关系数、χ²检验和Fisher精确检验分析了这些举措(2008 - 2010年和2011 - 2013年捐献时期)对关键报告点(6个月、1年、2年)合规性的影响。多变量逻辑回归模型测试了这些举措对患者随访可能性的影响。这些举措与表格报告合规性(r≥0.862,p≤0.027;1年和2年Fisher精确检验p≤0.002)和患者随访(χ²检验p≤0.009)的显著改善相关,且移植中心成本可接受。多变量分析表明,捐献时期与捐献后患者随访可能性的增加始终且显著相关(p < 0.001)。利用专门的项目资源实施绩效改进举措在财务上是可行的,并能带来更准确、完整的表格报告以及肾切除术后更好的患者随访。