Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 S. Fourth Street, Hamilton, MT 59840, USA.
Sci Transl Med. 2015 Apr 22;7(284):284fs16. doi: 10.1126/scitranslmed.aaa2817.
IFNλ restores blood-brain barrier integrity after disruption by West Nile virus, reducing virus invasion of the brain and increasing survival of infected mice (Lazear et al., this issue).
IFNλ 可修复西尼罗河病毒破坏的血脑屏障完整性,减少病毒对大脑的入侵,提高感染小鼠的存活率(Lazear 等人,本期)。