Bakula Marija, Mayer Miroslav, Čikeš Nada, Anić Branimir
Lijec Vjesn. 2015 Jan-Feb;137(1-2):27-9.
Rheumatoid arthritis and primary biliary cirrhosis coexist in up to 6% of cases. Tumor necrosis factor alpha seems to have an important role in the pathogenesis of both diseases. Tumor necrosis factor alpha inhibitors have become an established therapeutic regimen for patients with rheumatoid arthritis. The only approved drug for primary biliary cirrhosis is ursodeoxycholic acid. We describe the case of a female patient with both rheumatoid arthritis and primary biliary cirrhosis in a long term remission of both diseases induced with adalimumab. This case report is an important addendum to a few published similar reports.
类风湿性关节炎和原发性胆汁性肝硬化在高达6%的病例中同时存在。肿瘤坏死因子α似乎在这两种疾病的发病机制中都起着重要作用。肿瘤坏死因子α抑制剂已成为类风湿性关节炎患者的既定治疗方案。原发性胆汁性肝硬化唯一获批的药物是熊去氧胆酸。我们描述了一名患有类风湿性关节炎和原发性胆汁性肝硬化的女性患者的病例，该患者通过阿达木单抗实现了两种疾病的长期缓解。本病例报告是对一些已发表的类似报告的重要补充。
