Chandrasekaran Vasanthi, Dilara K, Padmavathi R
Indian J Physiol Pharmacol. 2014 Jul-Sep;58(3):206-10.
Tannery workers are at potential exposure to detrimental agents rendering them vulnerable to respiratory and dermal problems. Thus by performing pulmonary functions among leather tannery workers, we can decipher the effect of chromium and leather dust on lung functions and also the decline of respiratory functions with increasing years of exposure to leather dust. Pulmonary functions were assessed for 130 tannery workers and compared with the 130 unexposed office workers. Pulmonary function measurements namely FVC, FEV1, FEF25-75% and PEFR were measured using portable data logging Spirometer (KOKO Spirometer). The observed pulmonary functions of Tannery-workers in this study showed a reduction in FEV1, FVC, FEV1/FVC ratio, FEF25-75 and PEFR in relation to their predicted values and also compared to the unexposed. Smokers showed a decline in pulmonary functions compared to the non smokers because smoking acts as an additional risk factor in the development of respiratory illnesses. It is worthy to mention that the pulmonary function values correlate negatively with the duration of exposure to leather dust. So this study could provide base line information based upon which legal implementation of preventive measures could be undertaken.
制革工人有可能接触到有害制剂,这使他们易患呼吸道和皮肤问题。因此,通过对皮革制革厂工人进行肺功能检测,我们可以解读铬和皮革粉尘对肺功能的影响,以及随着接触皮革粉尘年限的增加呼吸功能的下降情况。对130名制革厂工人进行了肺功能评估,并与130名未接触的办公室工作人员进行了比较。使用便携式数据记录肺活量计(KOKO肺活量计)测量肺功能指标,即用力肺活量(FVC)、第一秒用力呼气容积(FEV1)、25%-75%用力呼气流量(FEF25-75%)和呼气峰值流速(PEFR)。本研究中观察到的制革厂工人的肺功能显示,与预测值相比,FEV1、FVC、FEV1/FVC比值、FEF25-75和PEFR均有所降低,与未接触者相比也是如此。吸烟者的肺功能与不吸烟者相比有所下降,因为吸烟是呼吸系统疾病发展中的一个额外风险因素。值得一提的是,肺功能值与接触皮革粉尘的持续时间呈负相关。因此,本研究可以提供基线信息,据此可以采取预防措施的法律实施。