细菌的多功能性需要 DEAD-box RNA 解旋酶。
Bacterial versatility requires DEAD-box RNA helicases.
机构信息
Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva, 1, rue Michel Servet, CH 1211 Geneva 4, Switzerland.
Department of Microbiology and Molecular Medicine, CMU, Faculty of Medicine, University of Geneva, 1, rue Michel Servet, CH 1211 Geneva 4, Switzerland
出版信息
FEMS Microbiol Rev. 2015 May;39(3):392-412. doi: 10.1093/femsre/fuv011. Epub 2015 Apr 22.
RNA helicases of the DEAD-box and DEAH-box families are important players in many processes involving RNA molecules. These proteins can modify RNA secondary structures or intermolecular RNA interactions and modulate RNA-protein complexes. In bacteria, they are known to be involved in ribosome biogenesis, RNA turnover and translation initiation. They thereby play an important role in the adaptation of bacteria to changing environments and to respond to stress conditions.
DEAD 盒和 DEAH 盒家族的 RNA 解旋酶是涉及 RNA 分子的许多过程中的重要参与者。这些蛋白质可以修饰 RNA 二级结构或分子间 RNA 相互作用，并调节 RNA-蛋白质复合物。在细菌中，它们已知参与核糖体生物发生、RNA 周转和翻译起始。因此，它们在细菌适应不断变化的环境和应对应激条件方面发挥着重要作用。
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