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在贝尔面瘫中,抗病毒药物相较于单独使用类固醇具有额外益处;对于未恢复的患者应考虑进行减压治疗。

Antiviral agents convey added benefit over steroids alone in Bell's palsy; decompression should be considered in patients who are not recovering.

作者信息

De Ru J A, Brennan P A, Martens E

机构信息

Department of Otolaryngology - Head and Neck Surgery,Central Military Hospital,Utrecht,the Netherlands.

Department of Oral and Maxillofacial Surgery,University of Portsmouth,UK.

出版信息

J Laryngol Otol. 2015 Apr;129(4):300-6. doi: 10.1017/S0022215115000341.

DOI:10.1017/S0022215115000341
PMID:25907276
Abstract

BACKGROUND

The management of Bell's palsy has been the subject of much debate, with corticosteroids being the preferred medication. However, evidence also supports the use of antiviral drugs for severe cases and even decompression surgery in patients who, despite medical treatment, are not recovering.

METHOD

A literature review was conducted on the management of Bell's palsy.

RESULTS

This paper describes the background, statistical evidence, study results and pathophysiological theories that support more aggressive treatment for patients with severe palsy and those who have inadequate recovery.

CONCLUSION

Combination therapy including antiviral medication significantly improves outcomes in patients with severe Bell's palsy. Decompression should be considered in patients who have not recovered with drug treatment.

摘要

背景

贝尔面瘫的治疗一直是诸多争论的主题,皮质类固醇是首选药物。然而,有证据也支持在严重病例中使用抗病毒药物,甚至对于那些尽管接受了药物治疗但仍未康复的患者可进行减压手术。

方法

对贝尔面瘫的治疗进行了文献综述。

结果

本文描述了支持对重症面瘫患者和恢复不佳患者采取更积极治疗的背景、统计学证据、研究结果及病理生理理论。

结论

包括抗病毒药物在内的联合治疗可显著改善重症贝尔面瘫患者的预后。对于药物治疗未康复的患者应考虑进行减压手术。

相似文献

1
Antiviral agents convey added benefit over steroids alone in Bell's palsy; decompression should be considered in patients who are not recovering.在贝尔面瘫中,抗病毒药物相较于单独使用类固醇具有额外益处;对于未恢复的患者应考虑进行减压治疗。
J Laryngol Otol. 2015 Apr;129(4):300-6. doi: 10.1017/S0022215115000341.
2
Bell's palsy.贝尔麻痹
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French Society of ENT (SFORL) guidelines. Management of acute Bell's palsy.法国耳鼻喉科学会(SFORL)指南。急性贝尔麻痹的管理
Eur Ann Otorhinolaryngol Head Neck Dis. 2020 Dec;137(6):483-488. doi: 10.1016/j.anorl.2020.06.004. Epub 2020 Jul 4.
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Bell's palsy.贝尔麻痹
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[Idiopathic facial nerve paralysis (Bell's palsy)].[特发性面神经麻痹(贝尔麻痹)]
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Antivirals in combination with corticosteroids compared to corticosteroids alone improve facial recovery in severe Bell's palsy… and possibly more?与单独使用皮质类固醇相比,抗病毒药物联合皮质类固醇可改善重度贝尔面瘫的面部恢复情况……可能还有更多益处?
Evid Based Med. 2015 Oct;20(5):178. doi: 10.1136/ebmed-2015-110271. Epub 2015 Aug 20.
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Clinical practice guideline: Bell's palsy.临床实践指南:贝尔氏麻痹。
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Do either corticosteroids or antiviral agents reduce the risk of long-term facial paresis in patients with new-onset Bell's palsy?皮质类固醇或抗病毒药物能否降低新发贝尔面瘫患者长期面部麻痹的风险?
J Emerg Med. 2010 May;38(4):518-23. doi: 10.1016/j.jemermed.2009.08.016. Epub 2009 Oct 21.
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A general practice approach to Bell's palsy.贝尔面瘫的一般诊疗方法。
Aust Fam Physician. 2016 Nov;45(11):794-797.
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Steroid plus antiviral treatment for Bell's palsy.类固醇联合抗病毒治疗贝尔麻痹。
J Intern Med. 2015 May;277(5):532-9. doi: 10.1111/joim.12288. Epub 2014 Aug 1.

引用本文的文献

1
Intratympanic steroid therapy for Bell's palsy with poor prognostic results.鼓室内类固醇治疗贝尔氏面瘫预后不良。
Sci Rep. 2021 Apr 13;11(1):8058. doi: 10.1038/s41598-021-87551-x.