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CNS injury: Microtubule stabilizer repairs spinal cord injury.

作者信息

Crunkhorn Sarah

出版信息

Nat Rev Drug Discov. 2015 May;14(5):310. doi: 10.1038/nrd4616. Epub 2015 Apr 24.

DOI:10.1038/nrd4616
PMID:25907343
Abstract
摘要

相似文献

1
CNS injury: Microtubule stabilizer repairs spinal cord injury.中枢神经系统损伤：微管稳定剂修复脊髓损伤。
Nat Rev Drug Discov. 2015 May;14(5):310. doi: 10.1038/nrd4616. Epub 2015 Apr 24.
2
Neuroscience. Systemically treating spinal cord injury.神经科学。脊髓损伤的全身治疗。
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Axonal regeneration. Systemic administration of epothilone B promotes axon regeneration after spinal cord injury.轴突再生。埃坡霉素B的全身给药可促进脊髓损伤后的轴突再生。
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4
Pharmacological Suppression of CNS Scarring by Deferoxamine Reduces Lesion Volume and Increases Regeneration in an In Vitro Model for Astroglial-Fibrotic Scarring and in Rat Spinal Cord Injury In Vivo.去铁胺对中枢神经系统瘢痕形成的药理学抑制作用可减小体外星形胶质细胞纤维化瘢痕模型及大鼠体内脊髓损伤模型中的损伤体积并促进再生。
PLoS One. 2015 Jul 29;10(7):e0134371. doi: 10.1371/journal.pone.0134371. eCollection 2015.
5
Enhanced regenerative axon growth of multiple fibre populations in traumatic spinal cord injury following scar-suppressing treatment.抑制瘢痕形成治疗后创伤性脊髓损伤中多种纤维群体的再生轴突生长增强。
Eur J Neurosci. 2009 Oct;30(8):1544-53. doi: 10.1111/j.1460-9568.2009.06929.x. Epub 2009 Oct 8.
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[Effect of chondroitinase ABC on axonal myelination and glial scar after spinal cord injury in rats].[软骨素酶ABC对大鼠脊髓损伤后轴突髓鞘形成及胶质瘢痕的影响]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2013 Feb;27(2):145-50.
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Complement protein C1q modulates neurite outgrowth in vitro and spinal cord axon regeneration in vivo.补体蛋白C1q在体外调节神经突生长，在体内调节脊髓轴突再生。
J Neurosci. 2015 Mar 11;35(10):4332-49. doi: 10.1523/JNEUROSCI.4473-12.2015.
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A self-assembling peptide reduces glial scarring, attenuates post-traumatic inflammation and promotes neurological recovery following spinal cord injury.自组装肽可减少神经胶质瘢痕形成，减轻创伤后炎症反应，促进脊髓损伤后的神经功能恢复。
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Pharmacologically inhibiting kinesin-5 activity with monastrol promotes axonal regeneration following spinal cord injury.使用莫那可林抑制驱动蛋白-5的活性可促进脊髓损伤后的轴突再生。
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Pharmacological modification of the extracellular matrix to promote regeneration of the injured brain and spinal cord.对细胞外基质进行药理学修饰以促进损伤的脑和脊髓再生。
Prog Brain Res. 2009;175:269-81. doi: 10.1016/S0079-6123(09)17518-0.

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The Protein Acetylation after Traumatic Spinal Cord Injury: Mechanisms and Therapeutic Opportunities.创伤性脊髓损伤后的蛋白质乙酰化：机制与治疗机遇
Int J Med Sci. 2024 Feb 12;21(4):725-731. doi: 10.7150/ijms.92222. eCollection 2024.
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14-3-3 protein augments the protein stability of phosphorylated spastin and promotes the recovery of spinal cord injury through its agonist intervention.14-3-3 蛋白通过激动剂干预增强磷酸化 spastin 的蛋白稳定性，促进脊髓损伤的恢复。
Elife. 2024 Jan 17;12:RP90184. doi: 10.7554/eLife.90184.
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Fibroblast Growth Factor 13 Facilitates Peripheral Nerve Regeneration through Maintaining Microtubule Stability.

本文引用的文献

1
Axonal regeneration. Systemic administration of epothilone B promotes axon regeneration after spinal cord injury.轴突再生。埃坡霉素B的全身给药可促进脊髓损伤后的轴突再生。
Science. 2015 Apr 17;348(6232):347-52. doi: 10.1126/science.aaa2958. Epub 2015 Mar 12.
成纤维细胞生长因子 13 通过维持微管稳定性促进周围神经再生。
Oxid Med Cell Longev. 2021 Aug 20;2021:5481228. doi: 10.1155/2021/5481228. eCollection 2021.
4
Upregulation of Apol8 by Epothilone D facilitates the neuronal relay of transplanted NSCs in spinal cord injury.表鬼臼素 D 通过上调 Apol8 促进移植神经干细胞在脊髓损伤中的神经元传递。
Stem Cell Res Ther. 2021 May 26;12(1):300. doi: 10.1186/s13287-021-02375-w.
5
Spastin interacts with collapsin response mediator protein 3 to regulate neurite growth and branching.痉挛素与塌陷反应介导蛋白3相互作用以调节神经突的生长和分支。
Neural Regen Res. 2021 Dec;16(12):2549-2556. doi: 10.4103/1673-5374.313052.
6
Mechanisms responsible for the inhibitory effects of epothilone B on scar formation after spinal cord injury.埃坡霉素B对脊髓损伤后瘢痕形成抑制作用的机制
Neural Regen Res. 2017 Mar;12(3):478-485. doi: 10.4103/1673-5374.202921.