Kojima Reiji, Ukawa Shigekazu, Ando Masahiko, Kawamura Takashi, Wakai Kenji, Tsushita Kazuyo, Tamakoshi Akiko
Department of Public Health, Hokkaido University Graduate School of Medicine, Hokkaido, Japan.
Department of Pediatrics, Japan Ground Self Defense Forces Sapporo Hospital, Hokkaido, Japan.
Geriatr Gerontol Int. 2016 Mar;16(3):384-91. doi: 10.1111/ggi.12487. Epub 2015 Apr 23.
To investigate the association between falls and self-reported depressive symptoms or visual impairment among young-old adults.
A total of 1904 participants (986 men and 918 women) aged 64 years from the New Integrated Suburban Seniority Investigation Project from 1996 to 2005, an age-specific cohort study in Nisshin, Japan, took part in the present study. Depressive symptoms were evaluated using the Geriatric Depression Scale. Visual impairment was assessed using a self-administered questionnaire. The outcome variable was self-reported injurious falls at the age of 70 years. Multivariate odds ratios (OR) and 95% confidence intervals (CI) of depressive symptoms and visual impairment for the incidence of falls were calculated using logistic regression models and adjusted for possible confounding factors.
Overall, 77 (7.8%) men and 126 (13.7%) women reported falls within the past 1 year at age 70 years. Among women, depressive symptoms and visual impairment were significantly associated with falls after adjusting for potential confounders (OR 1.70, 95% CI 1.09-2.62; OR 2.34, 95% CI 1.45-3.71, respectively), but not among men. Women with both conditions had a significantly increased risk of falls after adjusting for potential confounders (OR 3.50, 95% CI 1.65-7.13) compared with those with neither condition; the association was not significant among men.
Depressive symptoms and visual impairment at age 64 years were significantly associated with an increased risk of falls at age 70 years in Japanese women but not in men. The combination of the two symptoms had an even greater association with fall risk.
探讨年轻老年人跌倒与自我报告的抑郁症状或视力障碍之间的关联。
本研究纳入了1996年至2005年新综合郊区老年调查项目中的1904名64岁参与者（986名男性和918名女性），该项目是日本日新的一项特定年龄队列研究。使用老年抑郁量表评估抑郁症状。通过自我管理问卷评估视力障碍。结局变量是70岁时自我报告的伤害性跌倒。使用逻辑回归模型计算抑郁症状和视力障碍对跌倒发生率的多变量优势比（OR）和95%置信区间（CI），并对可能的混杂因素进行调整。
总体而言，77名（7.8%）男性和126名（13.7%）女性报告在70岁时过去1年内有跌倒。在女性中，调整潜在混杂因素后，抑郁症状和视力障碍与跌倒显著相关（OR分别为1.70，95%CI 1.09 - 2.62；OR为2.34，95%CI 1.45 - 3.71），但在男性中并非如此。调整潜在混杂因素后，同时患有这两种情况的女性跌倒风险显著增加（OR为3.50，95%CI 1.65 - 7.13），而两种情况都没有 的女性则不然；在男性中这种关联不显著。
64岁时的抑郁症状和视力障碍与日本女性70岁时跌倒风险增加显著相关，但与男性无关。这两种症状的组合与跌倒风险的关联更大。
