Kevetter G A, Perachio A A
Department of Otolaryngology, University of Texas Medical Branch, Galveston.
Brain Behav Evol. 1989;34(4):193-200. doi: 10.1159/000116505.
The projections of the saccule, an otolith end organ, to the cochlear nuclei were studied using both transganglionic transport and intracellular injection techniques. Labeled fibers and terminals were observed in the anterior and posterior portions of the ventral cochlear nucleus and the dorsal cochlear nucleus. Most terminals were present in the granule cell domain, especially in the subpeduncular corner between the anteroventral cochlear nucleus and the floccular peduncle of the cerebellum. It has been hypothesized that the cochlea in mammals may have developed phylogenetically from the saccule. The projections from the saccule to the cochlear nuclei were investigated in a mammalian species, the Mongolian gerbil, in an attempt to obtain initial information supporting or refuting this hypothesis. The presence of an otolith end organ projection to the cochlear nuclei in rodents should encourage comparative studies in additional aspects of the evolution of the auditory system.
使用跨神经节运输和细胞内注射技术，研究了耳石终器球囊向耳蜗核的投射。在腹侧耳蜗核和背侧耳蜗核的前部和后部观察到标记的纤维和终末。大多数终末存在于颗粒细胞区域，特别是在前庭蜗神经腹侧核与小脑绒球脚之间的脚周角。据推测，哺乳动物的耳蜗可能在系统发育上是从球囊发展而来的。在一种哺乳动物——蒙古沙鼠中，研究了球囊向耳蜗核的投射，试图获得支持或反驳这一假说的初步信息。啮齿动物中耳石终器向耳蜗核的投射的存在，应该会促进在听觉系统进化的其他方面进行比较研究。
