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与捐赠库奶和配方奶相比,主要采用生鲜母乳喂养低出生体重儿的效果更佳。

Improved outcomes of feeding low birth weight infants with predominantly raw human milk versus donor banked milk and formula.

作者信息

Dritsakou Kalliopi, Liosis Georgios, Valsami Georgia, Polychronopoulos Evangelos, Skouroliakou Maria

机构信息

a Departments of Quality Control, Research and Continuing Education , Elena Venizelou Maternity Hospital , Athens , Greece .

b Elena Venizelou Maternity Hospital , Athens , Greece .

出版信息

J Matern Fetal Neonatal Med. 2016;29(7):1131-8. doi: 10.3109/14767058.2015.1038232. Epub 2015 Apr 24.

Abstract

OBJECTIVES

To investigate the benefits of treating low birth weight infants predominantly with mother's own raw milk and early initiation of breastfeeding (raw human milk/breast-fed infants), in comparison to feeding only with donor banked milk (until the third week of life) and afterwards a preterm formula until hospital discharge (donor banked/formula-fed infants).

METHODS

One hundred and ninety-two predominantly raw human milk-fed infants (70% of raw and 30% of donor milk) were matched to 192 donor/formula-fed ones (on 1:1 ratio). Aggressive nutrition policy and targeted fortification of human milk were implemented in both groups.

RESULTS

The two groups show similar demographic and perinatal characteristics. Predominantly raw milk-fed infants regained earlier their birth weight, suffered less episodes of feeding intolerance and presented a higher body length and head circumference at discharge (p < 0.001). Those treated mainly with their mothers' milk were able to initiate breastfeeding almost 2 weeks earlier compared to those fed with donor milk who achieved to be bottle-fed later on post-conceptual age (p < 0.001). Infants being breastfed until the 8th month of life conducted less visits for a viral infection to a pediatrician compared to those in the other group (p < 0.001).

CONCLUSIONS

Feeding predominantly with mother's raw milk seems to result in optimal neonatal outcomes.

摘要

目的

研究与仅用捐赠母乳(直至出生后第三周)然后用早产配方奶喂养至出院(捐赠母乳/配方奶喂养婴儿)相比,以母亲自身的生鲜母乳为主并尽早开始母乳喂养(生鲜母乳/母乳喂养婴儿)对低出生体重婴儿的益处。

方法

192名以生鲜母乳为主喂养的婴儿(70%为生鲜母乳,30%为捐赠母乳)与192名捐赠母乳/配方奶喂养的婴儿(按1:1比例)进行匹配。两组均实施积极的营养政策和针对性的母乳强化。

结果

两组在人口统计学和围产期特征方面相似。以生鲜母乳为主喂养的婴儿体重恢复得更早,喂养不耐受发作次数更少,出院时身长和头围更大(p<0.001)。与用捐赠母乳喂养的婴儿相比,主要用母亲母乳治疗的婴儿能够提前近两周开始母乳喂养,而用捐赠母乳喂养的婴儿在孕龄后期才开始奶瓶喂养(p<0.001)。与另一组婴儿相比,母乳喂养至8个月的婴儿因病毒感染看儿科医生的次数更少(p<0.001)。

结论

以母亲的生鲜母乳为主进行喂养似乎能带来最佳的新生儿结局。

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