Dritsakou Kalliopi, Liosis Georgios, Valsami Georgia, Polychronopoulos Evangelos, Skouroliakou Maria
a Departments of Quality Control, Research and Continuing Education , Elena Venizelou Maternity Hospital , Athens , Greece .
b Elena Venizelou Maternity Hospital , Athens , Greece .
J Matern Fetal Neonatal Med. 2016;29(7):1131-8. doi: 10.3109/14767058.2015.1038232. Epub 2015 Apr 24.
To investigate the benefits of treating low birth weight infants predominantly with mother's own raw milk and early initiation of breastfeeding (raw human milk/breast-fed infants), in comparison to feeding only with donor banked milk (until the third week of life) and afterwards a preterm formula until hospital discharge (donor banked/formula-fed infants).
One hundred and ninety-two predominantly raw human milk-fed infants (70% of raw and 30% of donor milk) were matched to 192 donor/formula-fed ones (on 1:1 ratio). Aggressive nutrition policy and targeted fortification of human milk were implemented in both groups.
The two groups show similar demographic and perinatal characteristics. Predominantly raw milk-fed infants regained earlier their birth weight, suffered less episodes of feeding intolerance and presented a higher body length and head circumference at discharge (p < 0.001). Those treated mainly with their mothers' milk were able to initiate breastfeeding almost 2 weeks earlier compared to those fed with donor milk who achieved to be bottle-fed later on post-conceptual age (p < 0.001). Infants being breastfed until the 8th month of life conducted less visits for a viral infection to a pediatrician compared to those in the other group (p < 0.001).
Feeding predominantly with mother's raw milk seems to result in optimal neonatal outcomes.
研究与仅用捐赠母乳（直至出生后第三周）然后用早产配方奶喂养至出院（捐赠母乳/配方奶喂养婴儿）相比，以母亲自身的生鲜母乳为主并尽早开始母乳喂养（生鲜母乳/母乳喂养婴儿）对低出生体重婴儿的益处。
192名以生鲜母乳为主喂养的婴儿（70%为生鲜母乳，30%为捐赠母乳）与192名捐赠母乳/配方奶喂养的婴儿（按1:1比例）进行匹配。两组均实施积极的营养政策和针对性的母乳强化。
两组在人口统计学和围产期特征方面相似。以生鲜母乳为主喂养的婴儿体重恢复得更早，喂养不耐受发作次数更少，出院时身长和头围更大（p<0.001）。与用捐赠母乳喂养的婴儿相比，主要用母亲母乳治疗的婴儿能够提前近两周开始母乳喂养，而用捐赠母乳喂养的婴儿在孕龄后期才开始奶瓶喂养（p<0.001）。与另一组婴儿相比，母乳喂养至8个月的婴儿因病毒感染看儿科医生的次数更少（p<0.001）。
以母亲的生鲜母乳为主进行喂养似乎能带来最佳的新生儿结局。
