Jandoc Racquel, Jembere Nathaniel, Khan Saba, Russell Storm J, Allard Yvon, Cadarette Suzanne M
Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.
Arch Osteoporos. 2015;10:12. doi: 10.1007/s11657-015-0212-9. Epub 2015 Apr 25.
Half of Métis citizens, compared to less than 10 % of the general population of Ontario, reside in northern regions, with little access to bone mineral density (BMD) testing. Métis citizens had lower sex-specific and age-standardized rates of BMD testing, yet similar rates of fracture (both sexes) and pharmacotherapy (women only).
To examine osteoporosis management and common osteoporosis-related fractures among Métis citizens compared to the general population of older adults residing in Ontario.
We linked healthcare (medical and pharmacy) utilization and administrative (demographic) databases with the Métis Nation of Ontario citizenship registry to estimate osteoporosis management (bone mineral density [BMD] testing, pharmacotherapy) and fractures (hip, humerus, radius/ulna) among adults aged ≥50 years, from April 1, 2006 to March 31, 2011. Pharmacotherapy data were limited to residents aged ≥65 years. Sex-specific and age-standardized rates were compared between the Métis and the general population. Multivariable logistic regression was used to compare rates of BMD testing after controlling for differences in age and region of residence between the Métis and the general population.
We studied 4219 Métis citizens (55 % men), and 140 (3 %) experienced a fracture. Half of Métis citizens, compared to less than 10 % of the general population of Ontario, resided in northern regions. We identified significantly lower sex-specific and age-standardized rates of BMD testing among Métis compared to the general population, yet found little difference in fracture rates (both sexes) or pharmacotherapy (women only). Differences in BMD testing disappeared after adjusting for region of residence among women yet remained significant among men.
Despite finding significantly lower rates of osteoporosis management among men, Métis men and women were found to have similar age-standardized fracture rates to the general population.
与安大略省不到10%的普通人口相比,一半的梅蒂斯公民居住在北部地区,几乎无法进行骨密度(BMD)检测。梅蒂斯公民的BMD检测的性别特异性和年龄标准化率较低,但骨折(男女均有)和药物治疗(仅女性)的发生率相似。
与居住在安大略省的老年普通人群相比,研究梅蒂斯公民的骨质疏松症管理和常见的骨质疏松症相关骨折情况。
我们将医疗保健(医疗和药房)利用及行政(人口统计学)数据库与安大略省梅蒂斯民族公民登记处相链接,以估算2006年4月1日至2011年3月31日期间年龄≥50岁成年人的骨质疏松症管理情况(骨密度[BMD]检测、药物治疗)以及骨折情况(髋部、肱骨、桡骨/尺骨)。药物治疗数据仅限于年龄≥65岁的居民。比较了梅蒂斯人和普通人群之间的性别特异性和年龄标准化率。在控制了梅蒂斯人和普通人群之间年龄和居住地区差异后,使用多变量逻辑回归比较BMD检测率。
我们研究了4219名梅蒂斯公民(55%为男性),其中140人(3%)发生了骨折。与安大略省不到10%的普通人口相比,一半的梅蒂斯公民居住在北部地区。我们发现,与普通人群相比,梅蒂斯人的BMD检测的性别特异性和年龄标准化率显著较低,但骨折率(男女均有)或药物治疗(仅女性)几乎没有差异。在调整女性居住地区后,BMD检测的差异消失,但在男性中仍然显著。
尽管发现男性的骨质疏松症管理率显著较低,但梅蒂斯男性和女性的年龄标准化骨折率与普通人群相似。