Sari I, Aykent K, Davutoglu V, Yuce M, Ozer O, Kaplan M, Alici H, Ercan S, Sunbul M, Tigen K
Department of Cardiology, School of Medicine, Marmara University, Istanbul, Turkey,
Neth Heart J. 2015 May;23(5):265-74. doi: 10.1007/s12471-015-0688-3. Epub 2015 Apr 1.
We aimed to investigate whether there is an association between male pattern baldness and angiographic coronary artery disease (CAD) severity and collateral development, which has not been reported previously.
Coronary arteriograms, CAD risk factors, lipid parameters and presence and severity of baldness in 511 male patients were prospectively evaluated. Baldness was classified into five groups. Severity of CAD was evaluated with the Gensini scoring system and collateral development with Rentrop scores.
Although subjects with a higher Gensini score had more frequent and severe baldness, they were older than the group with lower Gensini scores. Bald patients had a higher Gensini score when compared with their non-bald counterparts. In univariate analysis, age more than 60, body mass index more than 30, smoking and baldness were predictors of high Gensini scores. In multivariate analysis, only age more than 60, body mass index more than 30 and smoking were independent predictors of a high Gensini score. There were no differences in terms of presence and severity of baldness in subjects with and without adequate collateral development.
There was no relation between presence, severity and age of occurrence of male pattern baldness and Gensini and Rentrop scores, which are important measures of presence and severity of CAD.
我们旨在研究男性型秃发与冠状动脉造影显示的冠心病(CAD)严重程度及侧支循环形成之间是否存在关联,此前尚无相关报道。
对511例男性患者的冠状动脉造影、CAD危险因素、血脂参数以及秃发的存在情况和严重程度进行前瞻性评估。秃发分为五组。CAD严重程度采用Gensini评分系统评估,侧支循环形成采用Rentrop评分评估。
尽管Gensini评分较高的受试者秃发更频繁且更严重,但他们的年龄比Gensini评分较低的组更大。与非秃发患者相比,秃发患者的Gensini评分更高。在单因素分析中,年龄大于60岁、体重指数大于30、吸烟和秃发是高Gensini评分的预测因素。在多因素分析中,只有年龄大于60岁、体重指数大于30和吸烟是高Gensini评分的独立预测因素。侧支循环形成充分和不充分的受试者在秃发的存在情况和严重程度方面没有差异。
男性型秃发的存在、严重程度和发病年龄与Gensini评分和Rentrop评分之间没有关系,而Gensini评分和Rentrop评分是CAD存在和严重程度的重要指标。