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术前额面QRS-T角是体外循环冠状动脉搭桥术后住院时间的独立相关因素及血流动力学支持需求的预测指标。

Preoperative frontal QRS-T angle is an independent correlate of hospital length of stay and predictor of haemodynamic support requirement following off-pump coronary artery bypass graft surgery.

作者信息

Kaya Erkan, Karabacak Kubilay, Kadan Murat, Gurses Kadri Murat, Kocyigit Duygu, Doganci Suat, Yildirim Vedat, Demirkilic Ufuk

机构信息

Department of Cardiovascular Surgery, Gulhane Military Medical Academy, Ankara, Turkey

Department of Cardiovascular Surgery, Gulhane Military Medical Academy, Ankara, Turkey.

出版信息

Interact Cardiovasc Thorac Surg. 2015 Jul;21(1):96-101. doi: 10.1093/icvts/ivv084. Epub 2015 Apr 23.

Abstract

OBJECTIVES

With the adoption of novel operative techniques and aggressive care protocols that facilitate earlier extubation and mobilization of patients, postoperative length of stay (LOS) following coronary artery bypass graft surgery (CABG) has declined. However, there is paucity of information regarding preoperative electrocardiographic predictors of LOS following CABG. In this study, we investigated whether frontal QRS-T angle, which is an abnormal repolarization marker in prediction of various cardiovascular events, was an independent correlate of postoperative hospital LOS for off-pump CABG. Furthermore, we evaluated independent predictors of vasopressor agent/intra-aortic balloon pump (IABP) support requirement following off-pump CABG.

METHODS

In this observational study, 78 patients with stable angina, who were scheduled for elective coronary artery bypass surgery following diagnosis of obstructive coronary artery disease by conventional angiography, were enrolled.

RESULTS

Left ventricular ejection fraction (LVEF) was significantly lower and vasopressor agent/IABP support requirement and incidence of sustained atrial or ventricular arrhythmias was higher in patients with wide QRS-T angle (P < 0.05). Postoperative hospital LOS was also longer in this group. From the preoperative characteristics, wide frontal QRS-T angle was found to be an independent correlate of postoperative hospital LOS (B ± SD: 11.97 ± 0.62, P ≤ 0.01). Wide frontal QRS-T angle was also found to be an independent predictor of vasopressor agent/IABP support requirement postoperatively (OR: 7.87, P ≤ 0.01).

CONCLUSIONS

Prediction of the hospital LOS and patient outcome following CABG is of great importance. Being easily obtainable via standard 12-lead electrocardiogram and its low cost may make frontal QRS-T angle a beneficial marker for reducing both patient-based morbidity and economic burden.

摘要

目的

随着新型手术技术和积极护理方案的采用,这些方案有助于患者更早拔管和活动,冠状动脉旁路移植术(CABG)后的术后住院时间(LOS)有所下降。然而,关于CABG术后住院时间的术前心电图预测指标的信息却很少。在本研究中,我们调查了额面QRS-T角,这是预测各种心血管事件的异常复极标志物,是否是非体外循环CABG术后住院时间的独立相关因素。此外,我们评估了非体外循环CABG术后血管升压药/主动脉内球囊泵(IABP)支持需求的独立预测因素。

方法

在这项观察性研究中,纳入了78例稳定型心绞痛患者,这些患者经传统血管造影诊断为阻塞性冠状动脉疾病后计划进行择期冠状动脉旁路手术。

结果

QRS-T角宽的患者左心室射血分数(LVEF)显著降低,血管升压药/IABP支持需求以及持续性房性或室性心律失常的发生率更高(P<0.05)。该组患者的术后住院时间也更长。从术前特征来看,额面QRS-T角宽被发现是术后住院时间的独立相关因素(B±SD:11.97±0.62,P≤0.01)。额面QRS-T角宽也被发现是术后血管升压药/IABP支持需求的独立预测因素(OR:7.87,P≤0.01)。

结论

预测CABG后的住院时间和患者预后非常重要。通过标准12导联心电图易于获得且成本低廉,这可能使额面QRS-T角成为降低基于患者的发病率和经济负担的有益标志物。

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