Liu Yang, Wei Li, Dong Ling, Zhu Mei-Ling, Tang Ming-Min, Zhang Lei
Zhongguo Zhong Yao Za Zhi. 2014 Dec;39(23):4479-83.
Based on the characteristics of multicomponent of traditional Chinese medicine and drawing lessons from the concepts, methods and techniques of biopharmaceutics classification system (BCS) in chemical field, this study comes up with the science framework of biopharmaceutics classification system of Chinese materia medica (CMMBCS). Using the different comparison method of multicomponent level and the CMMBCS method of overall traditional Chinese medicine, the study constructs the method process while setting forth academic thoughts and analyzing theory. The basic role of this system is clear to reveal the interaction and the related absorption mechanism of multicomponent in traditional Chinese medicine. It also provides new ideas and methods for improving the quality of Chinese materia medica and the development of new drug research.
基于中药多成分的特点，借鉴化学领域生物药剂学分类系统（BCS）的概念、方法和技术，本研究提出了中药生物药剂学分类系统（CMMBCS）的科学框架。采用多成分层面的不同比较方法以及整体中药的CMMBCS方法，本研究在阐述学术思想和分析理论的同时构建了方法流程。该系统的基本作用是清晰揭示中药中多成分的相互作用及相关吸收机制。它还为提高中药质量和新药研发提供了新的思路和方法。
