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产后出血干预时机与不良结局之间的关系。

The relationship between timing of postpartum hemorrhage interventions and adverse outcomes.

作者信息

Howard Tera F, Grobman William A

机构信息

Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL.

Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL.

出版信息

Am J Obstet Gynecol. 2015 Aug;213(2):239.e1-3. doi: 10.1016/j.ajog.2015.04.017. Epub 2015 Apr 23.

Abstract

OBJECTIVE

We sought to determine whether the timing of balloon tamponade (BT) and uterine artery embolization is associated with morbidity among women with postpartum hemorrhage (PPH).

STUDY DESIGN

This is a cohort study of women with PPH at a single tertiary academic institution. Patient demographics, delivery outcomes (eg, labor augmentation, route of delivery), and PPH-specific data (eg, estimated blood loss at the time when PPH interventions were employed) were abstracted from the chart. Outcomes studied included nadir hemoglobin, packed red blood cell transfusion, intensive care unit admission, and hysterectomy.

RESULTS

During the study period, 420 women were eligible for analysis. Women receiving BT at lower estimated blood loss quartiles had higher nadir hemoglobin, less frequent packed red blood cell transfusion, fewer intensive care unit admissions, and fewer hysterectomies. There were no associations found between timing of uterine artery embolization and maternal outcomes.

CONCLUSION

Earlier use of BT among women experiencing a PPH is associated with decreased maternal morbidity.

摘要

目的

我们试图确定球囊压迫止血(BT)和子宫动脉栓塞的时机是否与产后出血(PPH)女性的发病率相关。

研究设计

这是一项在单一三级学术机构对PPH女性进行的队列研究。从病历中提取患者人口统计学信息、分娩结局(如引产、分娩方式)和PPH特定数据(如采用PPH干预措施时的估计失血量)。研究的结局包括最低血红蛋白水平、红细胞输注、重症监护病房入院和子宫切除术。

结果

在研究期间,420名女性符合分析条件。在估计失血量较低四分位数时接受BT的女性,其最低血红蛋白水平较高,红细胞输注频率较低,重症监护病房入院次数较少,子宫切除术较少。未发现子宫动脉栓塞时机与产妇结局之间存在关联。

结论

PPH女性更早使用BT与产妇发病率降低相关。

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