针吸细胞学检查在可触及小儿肿瘤鉴别诊断中的作用

The role of needle aspiration cytology in the differential diagnosis of accessible paediatric tumours.

作者信息

Mwanda O W, Kitonyi G W, Owade J N, Njenga G, Kasili E G

出版信息

East Afr Med J. 1989 Mar;66(3):167-72.

Abstract

In the period 1985-88, 171 fine needle aspirates from paediatric patients with malignant and non-neoplastic masses were processed and evaluated in the Department of Haematology, Kenyatta National Hospital, Nairobi. Sixty-five needle aspirates had the diagnosis corroborated by histological reports. The rest had relevant clinical and laboratory information to support the cytological diagnosis. The histological diagnosis confirmed cytological diagnosis in 100% for neuroblastoma, 96% for Burkitt's lymphoma, 75% for carcinoma, 68% for sarcoma cases, 53% non-Hodgkin's lymphoma and 50% for Hodgkin's lymphoma. There were no false positives. It is therefore concluded that fine needle aspiration is a useful tool. It may obviate diagnostic surgery, help in planning the course of management of patients and it is diagnostic in Burkitt's lymphoma and neuroblastoma. Fine needle aspiration cytology is an easy, cheap and quick investigation compared to surgical biopsy.

摘要

1985年至1988年期间，内罗毕肯雅塔国家医院血液科对171例患有恶性和非肿瘤性肿块的儿科患者的细针穿刺抽吸物进行了处理和评估。65例针吸物的诊断得到了组织学报告的证实。其余的有相关临床和实验室信息支持细胞学诊断。组织学诊断在神经母细胞瘤中100%证实了细胞学诊断，伯基特淋巴瘤中为96%，癌为75%，肉瘤病例为68%，非霍奇金淋巴瘤为53%，霍奇金淋巴瘤为50%。没有假阳性。因此得出结论，细针穿刺抽吸是一种有用的工具。它可以避免诊断性手术，有助于规划患者的治疗方案，并且在伯基特淋巴瘤和神经母细胞瘤中具有诊断作用。与手术活检相比，细针穿刺抽吸细胞学检查是一种简单、廉价且快速的检查方法。