Bouchot O, Auvigne J, Peuvrel P, Glemain P, Buzelin J M
Clinique Urologique, Hôtel Dieu, Nantes, France.
Eur Urol. 1989;16(6):410-5. doi: 10.1159/000471632.
In the management of carcinoma of the penis, standard treatment of the primary tumor is by radiotherapy for small lesions (Tis, T1, T2 located in the glans) and by amputation in other cases (T2 with invasion of the shaft). The diagnosis and treatment of regional lymph nodes are thus the essential problems with this cancer. In our series of 45 patients with a minimum 5-year follow-up, clinical assessment was incorrect in 22.5% of cases (22% of the patients with negative bilateral biopsy of the superficial inguinal nodes developed metastases), and many of the complications (flap necrosis, lymphedema) occurring after inguinal lymphadenectomy contributed to a poorer quality of patient survival. A therapeutic approach to the management of regional lymph nodes in order to combat the carcinoma more effectively and improve patient survival quality is suggested.
在阴茎癌的治疗中,对于原发性肿瘤,标准治疗方法是:对于小病灶(Tis、T1、位于龟头的T2)采用放射治疗,其他情况(侵犯阴茎体的T2)则进行截肢。因此,区域淋巴结的诊断和治疗是这种癌症的关键问题。在我们对45例患者进行至少5年随访的系列研究中,临床评估在22.5%的病例中出现错误(22%双侧浅表腹股沟淋巴结活检阴性的患者发生了转移),腹股沟淋巴结切除术后出现的许多并发症(皮瓣坏死、淋巴水肿)导致患者生存质量较差。本文提出一种治疗区域淋巴结的方法,以便更有效地对抗癌症并提高患者生存质量。