单亚段内肝细胞癌的解剖性亚段切除术与非解剖性部分切除术的比较：一项单中心回顾性分析
Comparison between anatomical subsegmentectomy and nonanatomical partial resection for hepatocellular carcinoma located within a single subsegment: a single-center retrospective analysis.
作者信息
Yamamoto Takehito, Yagi Shintaro, Kita Ryosuke, Masui Hideyuki, Kinoshita Hiromitsu, Sakamoto Yusuke, Okada Kazuyuki, Miki Akira, Kondo Masato, Hashida Hiroki, Kobayashi Hiroyuki, Uryuhara Kenji, Kaihara Satoshi, Hosotani Ryo
出版信息
Hepatogastroenterology. 2015 Mar-Apr;62(138):363-7.
BACKGROUND/AIMS: For hepatocellular carcinoma (HCC) within a single subsegment, the superiority of anatomical subsegmentectomy over non-anatomical partial resection is still controversial. In this study, we assessed the potential benefit of subsegmentectomy.
METHODOLOGY
We selected 44 patients with a single HCC lesion within one subsegment who had undergone anatomical subsegmentectomy or non-anatomical partial resection from among 173 patients who underwent hepatectomy in our hospital from August 2003 to May 2013. We compared the results following anatomical subsegmentectomy (Group A; n = 16) and non-anatomical partial resection (Group N; n = 28).
RESULTS
One- and two-year survival rates were 92.5% and 89.3%, respectively; 1- and 2-year recurrence-free survival (RFS) rates were 88.9% and 69.1%, respectively. There was no significant difference in overall survival or RFS between the groups. However, among HBV-positive patients, RFS was significantly better for Group A than Group N (p = 0.008).
CONCLUSIONS
For HBV-positive HCC within a single subsegment, we recommend subsegmentectomy.
背景/目的：对于单个肝段内的肝细胞癌（HCC），解剖性肝段切除术相对于非解剖性部分切除术的优势仍存在争议。在本研究中，我们评估了肝段切除术的潜在益处。
方法
我们从2003年8月至2013年5月在我院接受肝切除术的173例患者中，选取了44例单个肝段内有单个HCC病灶且接受了解剖性肝段切除术或非解剖性部分切除术的患者。我们比较了解剖性肝段切除术组（A组；n = 16）和非解剖性部分切除术组（N组；n = 28）的结果。
结果
1年和2年生存率分别为92.5%和89.3%；1年和2年无复发生存率（RFS）分别为88.9%和69.1%。两组之间的总生存或RFS无显著差异。然而，在乙肝病毒（HBV）阳性患者中，A组的RFS显著优于N组（p = 0.008）。
结论
对于单个肝段内的HBV阳性HCC，我们推荐肝段切除术。
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