Claire Mayor-Dubois, Sophie Deglise, Claudia Poloni, Philippe Maeder, Eliane Roulet-Perez
a Pediatric Neurology and Neurorehabilitation Unit , University Hospital , Lausanne , Switzerland.
b Radiology Department , University Hospital , Lausanne , Switzerland.
Neurocase. 2016;22(1):45-54. doi: 10.1080/13554794.2015.1037843. Epub 2015 Apr 28.
The amygdala nuclei appear to be critically implicated in emotional memory. However, in most studies, encoding and consolidation processes cannot be analyzed separately. We thus studied the verbal emotional memory in a young woman with a ganglioglioma of the left amygdala and analyzed its impact (1) on each step of the memory process (encoding, retrieval, and recognition) (2) on short- and long-term consolidation (1-hour and 1-week delay) and (3) on processing of valence (positive and negative items compared to neutral words). Results showed emotional encoding impairments and, after encoding was controlled for, emotional long-term consolidation. Finally, although the negative words were not acknowledged as emotionally arousing by the patient, these words were specifically poorly encoded, recalled, and consolidated. Our data suggest that separate cerebral networks support the processing of emotional versus neutral stimuli.
杏仁核似乎在情绪记忆中起着关键作用。然而，在大多数研究中，编码和巩固过程无法分开分析。因此，我们研究了一名患有左侧杏仁核神经节胶质瘤的年轻女性的言语情绪记忆，并分析了其对记忆过程的每一步（编码、检索和识别）、短期和长期巩固（1小时和1周延迟）以及效价处理（与中性词相比的积极和消极项目）的影响。结果显示出情绪编码受损，在控制编码后，出现情绪长期巩固。最后，尽管患者并未将消极词汇视为具有情绪唤起作用，但这些词汇在编码、回忆和巩固方面表现出特别差的情况。我们的数据表明，不同的脑网络支持情绪刺激与中性刺激的处理。
