喀麦隆一家地区医院宫外孕后的生育情况。
Fertility after ectopic pregnancy in a district hospital in Cameroon.
作者信息
Kenfack Bruno, Nguefack-Tsague Georges, Ateudjeu Jerôme, Che Gilbert A, Mboudou Emile T
机构信息
Department of Biomedical Sciences, Faculty of Sciences, University of Dschang, Dschang, Cameroon.
Public Health Department, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
出版信息
Int J Gynaecol Obstet. 2015 Aug;130(2):165-8. doi: 10.1016/j.ijgo.2015.02.027. Epub 2015 Apr 18.
OBJECTIVE
To assess spontaneous conception after an ectopic pregnancy (EP) in a rural area of a low-resource country.
METHODS
The present prospective cohort study enrolled patients aged 15-45 years who were treated for EP at Sangmelima District Hospital, Cameroon, between January 2006 and December 2008. All patients who wished to become pregnant in the future were included and followed up from treatment for EP either until termination of a subsequent pregnancy or for 3 years if they did not become pregnant, whichever came first. Patients who were followed up for less than 18 months without a pregnancy were excluded from analysis.
RESULTS
The final analysis included 56 women, of whom 23 (41%) became pregnant (21 [38%] had intrauterine pregnancies, 2 [4%] EPs). The mean interval between treatment for EP and first conception was 11.82±7.46 months. In multivariate analysis, absence of contralateral adnexal pathology was significantly associated with higher fertility (hazard ratio 9.00, 95% confidence interval 1.48-54.67; P=0.017).
CONCLUSION
Fertility after EP in a rural area of Cameroon was found to be low, but recurrence of EP was rare.
目的
评估资源匮乏国家农村地区宫外孕（EP）后的自然受孕情况。
方法
本前瞻性队列研究纳入了2006年1月至2008年12月在喀麦隆桑梅利马区医院接受EP治疗的15 - 45岁患者。所有希望未来怀孕的患者均被纳入研究，并从EP治疗开始进行随访，直至后续妊娠终止，若未怀孕则随访3年，以先发生者为准。随访时间不足18个月且未怀孕的患者被排除在分析之外。
结果
最终分析纳入了56名女性，其中23名（41%）怀孕（21名[38%]为宫内妊娠，2名[4%]为宫外孕）。EP治疗与首次受孕之间的平均间隔为11.82±7.46个月。在多变量分析中，对侧附件无病变与较高的生育力显著相关（风险比9.00，95%置信区间1.48 - 54.67；P = 0.017）。
结论
喀麦隆农村地区EP后的生育力较低，但EP复发罕见。
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