Oh Soo-Yeon, Kim Na-Young, Oh Dong Hyun, Bang Soo Mee, Choi Yoon Jin, Lee Ju Yub, Lee Kyung Won, Yoon Ho Il, Yang Hee Chul, Paik Jin Ho, Lee Dong Ho, Jung Hyun Chae
Gut Liver. 2015 May 23;9(3):424-9. doi: 10.5009/gnl14072.
Herein, we report a rare case of concurrent gastric and pulmonary mucosa-associated lymphoid tissue (MALT) lymphomas. A 65-year-old man who had been diagnosed with -positive gastric MALT lymphoma received eradication therapy and achieved complete remission. During follow-up, he developed pulmonary MALT lymphoma as a sequela of pulmonary tuberculosis, accompanied by recurrent gastric MALT lymphoma. Polymerase chain reaction (PCR) products of the CDR3 region of the immunoglobulin heavy chain gene showed an overall polyclonal pattern with bands at 400 base pairs (bp) and 200 bp predominant in the pulmonary tissue, as well as two distinctive bands in the gastric tissue at 400 bp and 200 bp. This case suggests that multiorgan lymphomas are more likely to be independent from each other when they are far apart, involve different organ systems, and have independent precipitating factors.
在此，我们报告一例罕见的同时发生胃和肺黏膜相关淋巴组织（MALT）淋巴瘤的病例。一名65岁男性，曾被诊断为幽门螺杆菌阳性的胃MALT淋巴瘤，接受根除治疗后实现完全缓解。在随访期间，他因肺结核后遗症发展为肺MALT淋巴瘤，同时伴有复发性胃MALT淋巴瘤。免疫球蛋白重链基因CDR3区域的聚合酶链反应（PCR）产物显示出总体多克隆模式，在肺组织中以400碱基对（bp）和200 bp的条带为主，在胃组织中则有400 bp和200 bp两条独特的条带。该病例表明，多器官淋巴瘤在距离较远、涉及不同器官系统且有独立诱发因素时，更有可能相互独立。
