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基于胸腺瘀点出血的组织学发现对婴儿猝死综合征/非婴儿猝死综合征进行鉴别诊断。

Differential diagnosis SIDS/non-SIDS on the basis of histological findings of petechial thymus hemorrhages.

作者信息

Risse M, Weiler G

机构信息

Institute of Forensic Medicine, University Essen, F.R.G.

出版信息

Forensic Sci Int. 1989 Sep;43(1):1-7. doi: 10.1016/0379-0738(89)90115-1.

Abstract

Petechial thymus hemorrhages are found most frequently in SIDS (87%), and very much more rarely in fetuses after abortion and stillbirths (55%) as well as in perinatal deaths (40%). In these groups, there was a uniform histological bleeding pattern with emphasis on the cortical zone. In non-SIDS deaths of natural causes or extrinsic suffocation in babies and infants, it could be demonstrated in 39%. In extrinsic suffocation, the thymus hemorrhages were mostly less pronounced in quantitative terms than in SIDS. In non-SIDS (without extrinsic suffocation), a hemorrhage pattern different from SIDS could be detected with hemorrhagias of different sizes and irregularly distributed over the cortex and medulla.

摘要

瘀点性胸腺出血最常见于婴儿猝死综合征(87%),在流产和死产胎儿中则极为罕见(55%),在围产期死亡中也较少见(40%)。在这些群体中,存在一致的组织学出血模式,主要集中在皮质区。在自然原因导致的非婴儿猝死综合征死亡或婴儿和幼儿的外部窒息死亡中,这一比例为39%。在外部窒息中,胸腺出血在数量上大多不如婴儿猝死综合征明显。在非婴儿猝死综合征(无外部窒息)中,可以检测到与婴儿猝死综合征不同的出血模式,出血大小各异,不规则地分布在皮质和髓质。

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