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撒哈拉以南非洲地区新生儿肾母细胞瘤的罕见病例:资源有限地区的一例病例报告及处理

A rare occurrence of neonatal nephroblastoma in sub-saharan Africa: a case report and management in a resource-constrained region.

作者信息

Matondo Féfé Khuabi, Budiongo Aléine Nzazi, Tady Bruno Muyala, Lebwaze Bienvenu Massamba, Lelo Michel Tshikwela, Gini-Ehungu Jean Lambert, Mwepu Idesbald, Nkidiaka Emmanuel Dimbu, Aloni Michel Ntetani

机构信息

Division of Hematology/Oncology and Nephrology, Department of Pediatrics, University Hospital of Kinshasa School of Medicine, University of Kinshasa , Democratic Republic of Congo.

Division of Neonatology, Department of Pediatrics, University Hospital of Kinshasa School of Medicine, University of Kinshasa , Democratic Republic of Congo.

出版信息

Rare Tumors. 2015 Mar 26;7(1):5657. doi: 10.4081/rt.2015.5657. eCollection 2015 Feb 11.

Abstract

Neonatal nephroblastoma has been rarely reported in African neonate. A premature newborn (a 5-day-old male) was transferred with a history of neonatal abdominal mass. Ultrasonography revealed 75×46 mm, well-defined mass with mixed echogenicity replacing the right kidney. The patient underwent right radical nephrectomy and the tumor was confirmed to be a blastemal predominant Wilms' tumor by the histopathological examination and has an unfavorable prognosis. The child died secondary to multiple organ failure, three days after surgery. Our case report serves to remind us the need to bear in mind the possibility of the diagnosis of neonatal nephroblastoma in neonate with renal mass.

摘要

新生儿肾母细胞瘤在非洲新生儿中鲜有报道。一名早产新生儿(5日龄男性)因新生儿腹部肿块病史被转诊。超声检查显示一个75×46毫米、边界清晰、具有混合回声的肿块取代了右肾。患者接受了右侧根治性肾切除术,组织病理学检查证实肿瘤为以原始细胞为主的肾母细胞瘤,预后不良。患儿在术后三天死于多器官功能衰竭。我们的病例报告旨在提醒我们,对于有肾脏肿块的新生儿,需要牢记新生儿肾母细胞瘤的诊断可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c97e/4387355/40caa2e53886/rt-2015-1-5657-g001.jpg

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