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用狄诺塞麦治疗的复发性骨巨细胞瘤。

A recurrent giant cell tumor of bone treated with denosumab.

作者信息

Stadler Nicola, Fingernagel Thomas, Hofstaetter Stefan G, Trieb Klemens

机构信息

Department of Orthopaedics, Klinikum Wels-Grieskirchen , Wels, Austria.

出版信息

Clin Pract. 2015 Feb 10;5(1):697. doi: 10.4081/cp.2015.697. eCollection 2015 Jan 28.

DOI:10.4081/cp.2015.697
PMID:25918628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4387340/
Abstract

Although the giant cell tumor of bone is generally classified as a benign tumor it can rarely metastasize and has a potential risk of local recurrence. We want to report about a female patient who suffered from a recurrence of a giant cell tumor of bone after the implantation of a total endoprosthesis of the knee joint. We have treated her with denosumab, which is a receptor activator of nuclear factor kappa-B ligand inhibitor. In this case report we want to present a new option to treat this kind of neoplasm.

摘要

尽管骨巨细胞瘤通常被归类为良性肿瘤,但它很少会发生转移,并且存在局部复发的潜在风险。我们想要报告一位女性患者,她在膝关节全关节置换术后出现了骨巨细胞瘤复发。我们用狄诺塞麦对她进行了治疗,狄诺塞麦是一种核因子κB受体活化因子配体抑制剂。在本病例报告中,我们想介绍一种治疗这类肿瘤的新方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/348f/4387340/f85b68986ce4/cp-2015-1-697-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/348f/4387340/29ef7160b59d/cp-2015-1-697-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/348f/4387340/bb1690fc413e/cp-2015-1-697-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/348f/4387340/92ad4be89fc8/cp-2015-1-697-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/348f/4387340/f85b68986ce4/cp-2015-1-697-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/348f/4387340/29ef7160b59d/cp-2015-1-697-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/348f/4387340/bb1690fc413e/cp-2015-1-697-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/348f/4387340/92ad4be89fc8/cp-2015-1-697-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/348f/4387340/f85b68986ce4/cp-2015-1-697-g004.jpg

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