Angriman Marco, Caravale Barbara, Novelli Luana, Ferri Raffaele, Bruni Oliviero
Department of Pediatrics, Child Neurology and Neurorehabilitation Unit, Central Hospital of Bolzano, Italy.
Department of Developmental and Social Psychology, Sapienza University, Rome, Italy.
Neuropediatrics. 2015 Jun;46(3):199-210. doi: 10.1055/s-0035-1550151. Epub 2015 Apr 28.
This review describes recent research in pediatric sleep disorders associated with neurodevelopmental disabilities (NDDs) and their treatment. NDDs affect more than 2% of the general population and represent more than 35% of the total cases of children referred to a neuropsychiatric center for sleep problems. Specific clinical and therapeutic aspects of sleep disorders associated with Down syndrome, Fragile X syndrome, Prader-Willi syndrome, Angelman syndrome, Rett syndrome, Smith-Magenis syndrome, cerebral palsy, and autism spectrum disorders are described. Furthermore, the drugs commonly used for sleep disorders in children with NDDs are described. The review clearly highlighted that children with NDDs are often affected by sleep disorders that require appropriate clinical and therapeutic approach to improve quality of life in both patients and families.
本综述描述了与神经发育障碍（NDDs）相关的小儿睡眠障碍的近期研究及其治疗方法。神经发育障碍影响着超过2%的普通人群，在因睡眠问题转诊至神经精神科中心的儿童病例中占比超过35%。文中描述了与唐氏综合征、脆性X综合征、普拉德-威利综合征、天使综合征、雷特综合征、史密斯-马吉尼斯综合征、脑瘫和自闭症谱系障碍相关的睡眠障碍的具体临床和治疗方面。此外，还介绍了常用于患有神经发育障碍儿童睡眠障碍的药物。该综述明确强调，患有神经发育障碍的儿童常受睡眠障碍影响，需要采取适当的临床和治疗方法来改善患者及其家庭的生活质量。
