Grigoriadis Charalampos, Tympa Aliki, Theodoraki Kassiani
Invest Clin. 2015 Mar;56(1):66-73.
The progress in research of in vitro fertilization and fetal-maternal medicine allows more women and men, with fertility problems due to cystic fibrosis, to have a baby. In the majority of cases, pregnancy in women with cystic fibrosis results in favorable maternal and fetal outcomes. However, the incidence of preterm delivery, intrauterine growth restriction, caesarean section and deterioration of the maternal health are increased. Pre-pregnancy counseling is a crucial component of overall obstetric care, especially in women with poor pulmonary function. Additionally, closer monitoring during pregnancy with a multidisciplinary approach is required. The value of serial ultrasound scans and fetal Doppler assessment is important for the control of maternal and fetal wellbeing, as well as for the definition of the appropriate timing of delivery. In this article, clinical issues of pregnant women with cystic fibrosis are reviewed; counseling, obstetrical management and perinatal outcomes are being discussed.
体外受精和母胎医学研究的进展使更多因囊性纤维化而存在生育问题的男女能够生育。在大多数情况下，患有囊性纤维化的女性怀孕会产生良好的母婴结局。然而，早产、胎儿宫内生长受限、剖宫产以及孕产妇健康状况恶化的发生率有所增加。孕前咨询是整体产科护理的关键组成部分，尤其是对于肺功能较差的女性。此外，孕期需要采用多学科方法进行更密切的监测。连续超声扫描和胎儿多普勒评估对于控制母婴健康以及确定合适的分娩时机具有重要价值。本文回顾了患有囊性纤维化的孕妇的临床问题；并讨论了咨询、产科管理和围产期结局。
