Razavi Seyed Mohsen, Khodadost Mahmoud, Sohrabi Masoudreza, Keshavarzi Azam, Zamani Farhad, Rakhshani Naser, Ameli Mitra, Sadeghi Reza, Hatami Khadijeh, Ajdarkosh Hossein, Golmahi Zeynab, Ranjbaran Mehdi
Hematology and Oncology Department, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran E-mail :
Asian Pac J Cancer Prev. 2015;16(8):3141-5. doi: 10.7314/apjcp.2015.16.8.3141.
Gastric cancer (GC) is one the common lethal cancers in Iran. Detection of GC in the early stages would assesses to improve the survival of patients. In this study, we attempt to evaluate the accuracy of EUS in detection depth of invasion of GC among Iranian Patients.
This study is a retrospective study of patients with pathologically confirmed GC. They underwent EUS before initiating the treatment. The accuracy of EUS and agreement between the two methods was evaluated by comparing pre treatment EUS finding with post operative histopathological results.
The overall accuracy of EUS for T and N staging was 67.9% and 75.47, respectively. Underestimation and overestimation was seen in 22 (14.2%) and 40 (25.6%) respectively. The EUS was more accurate in large tumors and the tumors located in the middle and lower parts of the stomach. The EUS was more sensitive in T3 staging. The values of weighted Kappa from the T and N staging were 0.53 and 0.66, respectively.
EUS is a useful modality for evaluating the depth of invasion of GC. The accuracy of EUS was higher if the tumor was located in the lower parts of the stomach and the size of the tumor was more than 3 cm. Therefore, judgments made upon other criteria evaluated in this study need to be reconsidered.
胃癌（GC）是伊朗常见的致命癌症之一。早期检测胃癌有助于提高患者生存率。在本研究中，我们试图评估超声内镜（EUS）在伊朗患者中检测胃癌浸润深度的准确性。
本研究是一项对病理确诊为胃癌患者的回顾性研究。他们在开始治疗前接受了超声内镜检查。通过比较治疗前超声内镜检查结果与术后组织病理学结果，评估超声内镜的准确性以及两种方法之间的一致性。
超声内镜对T分期和N分期的总体准确率分别为67.9%和75.47%。分别有22例（14.2%）低估和40例（25.6%）高估。超声内镜对大肿瘤以及位于胃中下部的肿瘤更准确。超声内镜在T3分期中更敏感。T分期和N分期的加权Kappa值分别为0.53和0.66。
超声内镜是评估胃癌浸润深度的一种有用方法。如果肿瘤位于胃下部且肿瘤大小超过3厘米，超声内镜的准确性更高。因此，基于本研究中评估的其他标准所做的判断需要重新考虑。
