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常规使用止血带的静脉曲张手术后早期深静脉血栓形成的发生率及危险因素

Incidence and risk factors of early deep venous thrombosis after varicose vein surgery with routine use of a tourniquet.

作者信息

Chen Kai, Yu Guan-Feng, Huang Jing-Yong, Huang Li-Dong, Su Xiang, Ni Hai-Zhen, Pan Le-Men, Zheng Xiang-Tao

机构信息

Department of Vascular Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Department of Vascular Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

出版信息

Thromb Res. 2015 Jun;135(6):1052-6. doi: 10.1016/j.thromres.2015.03.008. Epub 2015 Mar 9.

Abstract

INTRODUCTION

The incidence of early deep venous thrombosis (DVT) following varicose vein surgery (traditional open stripping) with routine use of a tourniquet remains unknown.

MATERIALS AND METHODS

A retrospective analysis of all patients who underwent varicose vein surgery with a tourniquet in the authors' unit between 1 January 2012 and 30 November 2013 was undertaken. Cases of postoperative DVT were identified from the unit database, and re-assessments conducted 1, 3 and 6 months after the initial diagnosis were recorded from the outpatient department.

RESULTS

Out of 1461 patients, 113 (7.7%) developed postoperative DVT. Nineteen (1.3%) patients had proximal DVT, and 94 (6.4%) patients had isolated distal DVT. The risk factors for postoperative DVT included old age (≥65 years), female sex and gastrocnemius vein dilation (GVD). GVD was found to be a significant independent risk factor for the occurrence of DVT, with an odds ratio of 2.437 (95% confidence interval 1.644-3.611). Five patients with distal DVT (5.7%) and eight patients with proximal DVT (44.4%) still exhibited a thrombus at 6-month follow-up, but with decreased size and at various stages of resolution.

CONCLUSIONS

This study found a higher incidence of postoperative DVT (7.7%) with routine use of a tourniquet during varicose vein surgery than has been reported previously. Among the factors examined, GVD had the highest predictive power for postoperative DVT. Both distal and proximal DVT were associated with acceptable outcomes.

摘要

引言

在常规使用止血带的情况下,静脉曲张手术(传统开放式剥脱术)后早期深静脉血栓形成(DVT)的发生率尚不清楚。

材料与方法

对2012年1月1日至2013年11月30日期间在作者所在科室接受使用止血带的静脉曲张手术的所有患者进行回顾性分析。从科室数据库中识别出术后DVT病例,并记录门诊在初次诊断后1、3和6个月进行的重新评估。

结果

1461例患者中,113例(7.7%)发生术后DVT。19例(1.3%)患者发生近端DVT,94例(6.4%)患者发生孤立性远端DVT。术后DVT的危险因素包括老年(≥65岁)、女性和腓肠肌静脉扩张(GVD)。发现GVD是DVT发生的一个重要独立危险因素,比值比为2.437(95%置信区间1.644 - 3.611)。5例远端DVT患者(5.7%)和8例近端DVT患者(44.4%)在6个月随访时仍有血栓,但血栓大小减小且处于不同的溶解阶段。

结论

本研究发现,静脉曲张手术期间常规使用止血带时,术后DVT的发生率(7.7%)高于先前报道。在所研究的因素中,GVD对术后DVT的预测能力最高。远端和近端DVT均与可接受的结果相关。

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