Patel Jignesh K, Schoenfeld Elinor, Parnia Sam, Singer Adam J, Edelman Norman
Division of Pulmonary and Critical Care, Department of Medicine, Stony Brook University Medical Center, Stony Brook, NY, USA
Department of Preventive Medicine, Stony Brook University Medical Center, Stony Brook, NY, USA.
J Intensive Care Med. 2016 Jul;31(6):359-68. doi: 10.1177/0885066615583651. Epub 2015 Apr 28.
Cardiac arrest (CA) is a major cause of morbidity and mortality worldwide. Despite the use of conventional cardiopulmonary resuscitation (CPR), rates of return of spontaneous circulation and survival with minimal neurologic impairment remain low. Utilization of venoarterial extracorporeal membrane oxygenation (ECMO) for CA in adults is steadily increasing. Propensity-matched cohort studies have reported outcomes associated with ECMO use to be superior to that of conventional CPR alone in in-hospital patients with CA. In this review, we discuss the mechanism, indications, complications, and evidence for ECMO in CA in adults.
心脏骤停(CA)是全球发病和死亡的主要原因。尽管使用了传统的心肺复苏(CPR),自主循环恢复率和伴有轻微神经功能障碍的生存率仍然很低。成人CA患者使用静脉-动脉体外膜肺氧合(ECMO)的情况正在稳步增加。倾向匹配队列研究报告称,在住院的CA患者中,使用ECMO的结果优于单独使用传统CPR。在这篇综述中,我们讨论了成人CA患者使用ECMO的机制、适应症、并发症及相关证据。