Division of Infectious Diseases, Wayne State University, Detroit, Michigan.
R M Alden Research Laboratory, Santa Monica, California David Geffen School of Medicine at the University of California, Los Angeles.
Clin Infect Dis. 2015 May 15;60 Suppl 2:S72-6. doi: 10.1093/cid/civ053.
Across the United States, the baby boomers are entering into their elderly years. As they are America's largest generation to do so to date, their need for care will greatly affect nursing homes, long-term care facilities, and long-term acute-care hospitals (LTACHs). Unfortunately, the rise of Clostridium difficile infection (CDI), particularly in extended-care facilities, might become the biggest obstacle in their care. Elderly extended-care-facility residents are at an elevated risk of CDI simply due to their advanced age and the fact that they are receiving care in an extended-care facility. LTACHs experience a high incidence rate of CDI, and these infections can lead to major complications for a patient's health. Other factors that contribute to higher risk for CDI include receiving multiple courses of antibiotics, longer length of antibiotic treatment, and previous CDI. Although this obstacle to proper care is great, some simple solutions are available to healthcare providers. Probiotics may help improve natural immunity in patients, and strict adherence to antimicrobial stewardship standards could help reduce this serious bacterial threat.
在美国,婴儿潮一代正步入老年。由于他们是迄今为止美国最大的一代人,他们对护理的需求将极大地影响疗养院、长期护理机构和长期急性护理医院 (LTACH)。不幸的是,艰难梭菌感染 (CDI) 的上升,特别是在长期护理机构,可能成为他们护理的最大障碍。由于高龄和在长期护理机构接受护理,老年长期护理机构居民感染 CDI 的风险更高。LTACH 经历了 CDI 的高发率,这些感染会导致患者健康出现重大并发症。导致 CDI 风险增加的其他因素包括接受多疗程抗生素治疗、抗生素治疗时间延长和以前有过 CDI。尽管这对适当护理是一个巨大的障碍,但医疗保健提供者可以采取一些简单的解决方案。益生菌可能有助于改善患者的自然免疫力,严格遵守抗菌药物管理标准有助于减少这种严重的细菌威胁。