Gao Feng, Ge Xiaojun, Li Ming, Zheng Xiangpeng, Xiao Li, Zhang Guozhen, Hua Yanqing
1 Department of Radiology, 2 Diagnostic and Treatment Center of Small Lung Nodules, 3 Department of Pathology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.
J Thorac Dis. 2015 Mar;7(3):273-80. doi: 10.3978/j.issn.2072-1439.2015.02.07.
To explore the CT features of lung scar cancer (LSC).
CT images of 41 LSCs and 66 non-LSCs were retrospectively compared in terms of location, size, shape, border, speculation, lobulation, pleural indentation, surrounding ground-glass opacification (sGGO), vessel convergence, vacuolation, calcification and satellite opacification.
Thirty-eight LSCs were histopathologically identified as adenocarcinoma. The LSCs and non-LSCs were located 8.73±8.65 and 12.55±10.67 mm from the pleura, respectively. The mean lesion sizes (3-D ratios) in the initial LSC, pre-surgical LSC and non-LSC images were 24.28±6.29 (0.33±0.65), 32.23±8.14 (0.60±0.18) and 23.24±3.73 (0.35±0.61) mm, respectively. The initial and pre-surgical LSC images showed significant differences in speculation and sGGO (P<0.05). Significant differences were also noted in vacuolation, vessel convergence and sGGO between the pre-surgical LSC and the non-LSC images (P<0.05) and in vacuolation between the initial LSC and the non-LSC images (P<0.05).
Despite similar CT features of LSCs and non-LSCs, the early detection and diagnosis of LSCs is possible by studying scar-tissue changes such as enlargement and sGGO associated with well-defined lesion borders in follow-up CT images.
探讨肺瘢痕癌（LSC）的CT特征。
回顾性比较41例LSC和66例非LSC的CT图像，比较其位置、大小、形态、边界、毛刺、分叶、胸膜凹陷、周围磨玻璃样混浊（sGGO）、血管集束、空泡征、钙化及卫星灶。
38例LSC经组织病理学确诊为腺癌。LSC和非LSC距胸膜的距离分别为8.73±8.65和12.55±10.67mm。LSC初始图像、术前图像及非LSC图像的平均病变大小（三维径线）分别为24.28±6.29（0.33±0.65）、32.23±8.14（0.60±0.18）和23.24±3.73（0.35±0.61）mm。LSC初始图像和术前图像在毛刺和sGGO方面差异有统计学意义（P<0.05）。术前LSC图像与非LSC图像在空泡征、血管集束和sGGO方面差异有统计学意义（P<0.05），初始LSC图像与非LSC图像在空泡征方面差异有统计学意义（P<0.05）。
尽管LSC与非LSC的CT特征有相似之处，但通过研究随访CT图像中瘢痕组织的变化，如与边界清晰的病变相关的增大和sGGO，LSC的早期检测和诊断是可能的。
