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开放性痔切除术后意外发生的肛管鳞状细胞癌。

Unexpected anal squamous cells carcinoma after open hemorrhoidectomy.

作者信息

Luca Navarra, Valentina Abruzzese, Federico Sista, Renato Pietroletti

机构信息

Department of Surgery, SS. Trinità Hospital, Via Enrico Berlinguer, 65026 Popoli, Italy.

Dipartimento di Scienze Cliniche Applicate e Biotecnologie, University of L'Aquila, Viale dell'Ospedale Edificio Delta 6, 67100 L'Aquila, Italy.

出版信息

Case Rep Surg. 2015;2015:616274. doi: 10.1155/2015/616274. Epub 2015 Apr 2.

DOI:10.1155/2015/616274
PMID:25922781
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4398956/
Abstract

We report a case of unexpected anal squamous cells carcinoma found in hemorrhoidectomy specimen. The patient had a 3-year history of prolapsing hemorrhoids. A prolapsing hemorrhoid was present at eleven o'clock in lithotomy. Milligan-Morgan was performed and gross examination of the specimen was unremarkable. Histopathologic evaluation showed noninvasive squamous cells carcinoma. The present case report evidences the opportunity of routine histopathologic analysis of hemorrhoidal specimens particularly in case of long-standing prolapse. Questions arise in the option of those techniques where no specimens are collected or tissue is excised far from deceased area.

摘要

我们报告了一例在痔切除术标本中意外发现的肛管鳞状细胞癌病例。该患者有3年痔脱垂病史。截石位时,在11点处可见一个脱垂痔。进行了Milligan-Morgan手术,标本大体检查未见异常。组织病理学评估显示为非浸润性鳞状细胞癌。本病例报告证明了对痔标本进行常规组织病理学分析的必要性,特别是在长期脱垂的情况下。对于那些未采集标本或切除组织远离病变区域的技术选择,也引发了一些问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b07/4398956/07beb1cbe106/CRIS2015-616274.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b07/4398956/07beb1cbe106/CRIS2015-616274.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b07/4398956/07beb1cbe106/CRIS2015-616274.001.jpg

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本文引用的文献

1
Incidental rectal carcinoid discovered after stapled hemorrhoidopexy: importance of histopathologic examination.吻合器痔上黏膜环切术术后偶然发现的直肠类癌:组织病理学检查的重要性
Ann Ital Chir. 2011 Mar-Apr;82(2):155-7.
2
Elevated anal squamous cell carcinoma risk associated with benign inflammatory anal lesions.与良性炎性肛门病变相关的肛门鳞状细胞癌风险升高。
Gut. 2006 May;55(5):703-7. doi: 10.1136/gut.2005.070201. Epub 2005 Nov 18.
3
Risk factors for anal cancer: results of a population-based case--control study.肛门癌的危险因素:一项基于人群的病例对照研究结果
Cancer Causes Control. 2003 Nov;14(9):837-46. doi: 10.1023/b:caco.0000003837.10664.7f.
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Anal carcinoma or "just hemorrhoids"?肛管癌还是“仅仅是痔疮”?
Am Surg. 2001 Nov;67(11):1048-58.
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Pagetoid dyskeratosis is a frequent incidental finding in hemorrhoidal disease.派杰样角化不良是痔病中常见的偶然发现。
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Adenocarcinoma in a hemorrhoidectomy specimen: case report and review of the literature.痔切除术标本中的腺癌:病例报告及文献综述
Am Surg. 2000 Aug;66(8):789-92.
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Benign anal lesions, inflammatory bowel disease and risk for high-risk human papillomavirus-positive and -negative anal carcinoma.良性肛门病变、炎症性肠病与高危人乳头瘤病毒阳性和阴性肛门癌的风险
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Unsuspected carcinoma found histologically after minor anorectal operations.在小型肛肠手术后经组织学检查发现的意外癌。
Calif Med. 1967 Jan;106(1):44-8.
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Intraepithelial neoplasia of the anal canal in hemorrhoidal tissue: a study of 19 cases.痔组织中肛管上皮内瘤变:19例研究
Hum Pathol. 1991 Jun;22(6):528-34. doi: 10.1016/0046-8177(91)90228-h.