猴子和大鼠不易感染雪貂戊型肝炎病毒。
Monkeys and Rats Are Not Susceptible to Ferret Hepatitis E Virus Infection.
作者信息
Li Tian-Cheng, Yoshizaki Sayaka, Ami Yasushi, Suzaki Yuriko, Yang Tingting, Takeda Naokazu, Takaji Wakita
机构信息
Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan.
出版信息
Intervirology. 2015;58(3):139-42. doi: 10.1159/000373891. Epub 2015 Apr 30.
Ferret hepatitis E virus (HEV), a novel hepatitis E-like virus, has been identified in ferrets in the Netherlands, Japan, and the US. To determine whether ferret HEV transmits to other animals, we inoculated laboratory rats (Wistar), nude rats (Long-Evans-rnu/rnu), and cynomolgus monkeys with ferret HEV (F4351) by intravenous injection. None of the animals demonstrated a positive sign for virus replication, indicating that rats and monkeys are not susceptible to ferret HEV.
雪貂戊型肝炎病毒（HEV）是一种新型的类戊型肝炎病毒，已在荷兰、日本和美国的雪貂中被发现。为了确定雪貂HEV是否会传染给其他动物，我们通过静脉注射，用雪貂HEV（F4351）接种了实验大鼠（Wistar）、裸鼠（Long-Evans-rnu/rnu）和食蟹猴。没有一只动物表现出病毒复制的阳性迹象，这表明大鼠和猴子对雪貂HEV不敏感。
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