Baker IDI Heart and Diabetes Institute, Post Office Box 6492, St. Kilda Road Central, Melbourne, Victoria, Australia.
Sci Transl Med. 2015 Apr 29;7(285):285fs18. doi: 10.1126/scitranslmed.aaa5457.
Renal sympathetic denervation with intravascular radiofrequency catheters in hypertensive patients is less effective than anticipated, owing to radio frequency energy being applied to a part of the renal artery where the nerves are at the greatest distance from the aortic lumen and to distortion of energy distribution and temperature gradients by regional tissue anatomical variations (Tzafriri et al., this issue).
由于射频能量施加到肾动脉的一部分,那里的神经距离主动脉腔最远,并且由于区域组织解剖变异(Tzafriri 等人,本期)导致能量分布和温度梯度的扭曲,使用血管内射频导管对高血压患者进行肾脏去交感神经支配的效果不如预期的那么有效。