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肾脏去神经术:并不像看上去那么简单。

Renal denervation: Not as easy as it looks.

机构信息

Baker IDI Heart and Diabetes Institute, Post Office Box 6492, St. Kilda Road Central, Melbourne, Victoria, Australia.

出版信息

Sci Transl Med. 2015 Apr 29;7(285):285fs18. doi: 10.1126/scitranslmed.aaa5457.

DOI:10.1126/scitranslmed.aaa5457
PMID:25925679
Abstract

Renal sympathetic denervation with intravascular radiofrequency catheters in hypertensive patients is less effective than anticipated, owing to radio frequency energy being applied to a part of the renal artery where the nerves are at the greatest distance from the aortic lumen and to distortion of energy distribution and temperature gradients by regional tissue anatomical variations (Tzafriri et al., this issue).

摘要

由于射频能量施加到肾动脉的一部分,那里的神经距离主动脉腔最远,并且由于区域组织解剖变异(Tzafriri 等人,本期)导致能量分布和温度梯度的扭曲,使用血管内射频导管对高血压患者进行肾脏去交感神经支配的效果不如预期的那么有效。

相似文献

1
Renal denervation: Not as easy as it looks.肾脏去神经术:并不像看上去那么简单。
Sci Transl Med. 2015 Apr 29;7(285):285fs18. doi: 10.1126/scitranslmed.aaa5457.
2
Arterial microanatomy determines the success of energy-based renal denervation in controlling hypertension.动脉微观解剖结构决定了基于能量的肾去神经术在控制高血压方面的成效。
Sci Transl Med. 2015 Apr 29;7(285):285ra65. doi: 10.1126/scitranslmed.aaa3236.
3
Hypotensive effects of renal denervation in spontaneously hypertensive rat based on ultrasonic contrast imaging.基于超声对比成像的自发性高血压大鼠肾去神经降压作用。
Comput Med Imaging Graph. 2017 Jun;58:56-61. doi: 10.1016/j.compmedimag.2017.01.006. Epub 2017 Feb 9.
4
Renal denervation using focused infrared fiber lasers: a potential treatment for hypertension.使用聚焦红外光纤激光器进行肾去神经支配:一种治疗高血压的潜在方法。
Lasers Surg Med. 2014 Nov;46(9):689-702. doi: 10.1002/lsm.22290. Epub 2014 Aug 29.
5
The role of renal sympathetic nerves in hypertension: has percutaneous renal denervation refocused attention on their clinical significance?肾交感神经在高血压中的作用:经皮肾去神经术是否重新引起了人们对其临床意义的关注?
Prog Cardiovasc Dis. 2009 Nov-Dec;52(3):243-8. doi: 10.1016/j.pcad.2009.09.003.
6
The morphological substrate for Renal Denervation: Nerve distribution patterns and parasympathetic nerves. A post-mortem histological study.肾去神经支配的形态学基础:神经分布模式与副交感神经。一项尸检组织学研究。
Ann Anat. 2016 Mar;204:71-9. doi: 10.1016/j.aanat.2015.11.004. Epub 2015 Nov 23.
7
The future of renal denervation.肾去神经支配的未来。
Auton Neurosci. 2017 May;204:131-138. doi: 10.1016/j.autneu.2016.08.004. Epub 2016 Aug 3.
8
The temperature field simulation of radiofrequency catheter-based renal sympathetic denervation for resistant hypertension.基于射频导管的肾交感神经去支配术治疗顽固性高血压的温度场模拟
Biomed Mater Eng. 2014;24(1):315-21. doi: 10.3233/BME-130813.
9
Hypertension: Microanatomy impacts on RDN.
Nat Rev Nephrol. 2015 Jul;11(7):387. doi: 10.1038/nrneph.2015.80. Epub 2015 May 19.
10
Recent developments in renal denervation.肾去神经支配的最新进展
Minerva Cardioangiol. 2013 Jun;61(3):271-80.

引用本文的文献

1
Renal denervation for resistant hypertension.肾动脉去神经术治疗耐药性高血压。
Cochrane Database Syst Rev. 2021 Nov 22;11(11):CD011499. doi: 10.1002/14651858.CD011499.pub3.
2
Renal Innervation in Resistant Hypertension: A Review of Pathophysiology and Renal Denervation as Potential Treatment.顽固性高血压中的肾神经支配:病理生理学及肾去神经术作为潜在治疗方法的综述
Curr Hypertens Rev. 2020;16(2):115-127. doi: 10.2174/1573402115666190301154100.
3
Renal denervation for resistant hypertension.肾去神经术治疗顽固性高血压。
Cochrane Database Syst Rev. 2017 Feb 21;2(2):CD011499. doi: 10.1002/14651858.CD011499.pub2.
4
Interventional procedures and future drug therapy for hypertension.高血压的介入治疗及未来药物治疗
Eur Heart J. 2017 Apr 14;38(15):1101-1111. doi: 10.1093/eurheartj/ehw303.
5
Renal Denervation for the Hypertension of Chronic Kidney Disease: A Special Case?肾去神经支配治疗慢性肾脏病高血压:一种特殊情况?
J Clin Hypertens (Greenwich). 2016 Mar;18(3):187-9. doi: 10.1111/jch.12730. Epub 2015 Dec 31.