Shulman K I, Walker S E, MacKenzie S, Knowles S
Department of Psychiatry University of Toronto, Ontario, Canada.
J Clin Psychopharmacol. 1989 Dec;9(6):397-402.
The aim of this study is to provide clearer guidelines for rational, safe, and practical dietary restriction for use with monoamine oxidase inhibitors. Tyramine levels were assayed in over 100 of the controversial foods that have been associated with hypertensive reactions or reported to contain high levels of tyramine. Only a very limited number of foods appear to require absolute restriction. These include all aged cheeses, concentrated yeast extracts (e.g., Marmite), sauerkraut, and broad bean pods. Alcoholic beverages, including Chianti wine consumed in moderation, appear to be safe. Some aged meats contain relatively high levels of tyramine and require closer investigation.
本研究的目的是为与单胺氧化酶抑制剂联合使用时合理、安全且实用的饮食限制提供更清晰的指导方针。对100多种有争议的食物进行了酪胺水平检测，这些食物曾与高血压反应有关或据报道含有高酪胺水平。似乎只有极少数食物需要绝对限制。这些食物包括所有陈年奶酪、浓缩酵母提取物（如马麦脱酸酵母）、德国泡菜和蚕豆荚。包括适量饮用的基安蒂葡萄酒在内的酒精饮料似乎是安全的。一些陈年肉类含有相对较高水平的酪胺，需要进一步调查。
