Properties and clinical utility of topotecan fluorescence: uses for retinoblastoma.
作者信息
Francis Jasmine H, Marr Brian P, Schaiquevich Paula, Kellick Michael G, Abramson David H
机构信息
Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA Department of Ophthalmology, Weill Cornea Medical Center, New York, New York, USA.
Unidad de Farmacocinética Clínica, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina.
出版信息
Br J Ophthalmol. 2015 Oct;99(10):1320-2. doi: 10.1136/bjophthalmol-2015-306633. Epub 2015 Apr 29.
Topotecan fluoresces when exposed to ultraviolet (UV) light. Our observations with UV light in retinoblastoma cases has allowed us to minimise and manage inadvertent skin contact, guide periocular injections and leakage from such injections and document conjunctival contact after periocular injection in addition to demonstrating the drug in the vitreous after intravitreal injection. The technique is safe, inexpensive and easy to perform.
Zotero 插件