Ohman A, Ohlund L S, Alm T, Wieselgren I M, Ost L G, Lindström L H
J Abnorm Psychol. 1989 Nov;98(4):426-35. doi: 10.1037//0021-843x.98.4.426.
The hypothesis that electrodermal nonresponsiveness to orienting stimuli delineates a core group of "Kraepelinian" type schizophrenics was tested by following up social functioning outcome over a 2-year period in 37 schizophrenics. Good social functioning outcome required both some self-supporting ability in the job market and a minimal social life. The prior assessments included monitoring of electrodermal responses to a series of moderately intense tones, ratings of reported and observed symptoms during an interview, and ratings of premorbid adjustment on the basis of an interview with a close relative. Electrodermal nonresponding, poor premorbid adjustment, and negative symptomatology predicted poor social functioning during the second follow-up year, but the relationship to nonresponding pertained exclusively to a group of 15 first-episode patients. Discriminant analysis showed that electrodermal nonresponding and symptoms were the only independent predictors of outcome.
通过对37名精神分裂症患者进行为期两年的社会功能结果随访，检验了如下假设：对定向刺激无皮肤电反应描绘出一组核心的“克雷佩林式”精神分裂症患者。良好的社会功能结果要求在就业市场具备一定的自我支持能力以及最低限度的社交生活。先前的评估包括监测对一系列中等强度音调的皮肤电反应、访谈期间对报告和观察到的症状进行评分，以及根据与近亲的访谈对病前适应情况进行评分。皮肤电无反应、病前适应不良和阴性症状预示着第二次随访年度社会功能较差，但无反应与社会功能较差的关系仅适用于一组15名首发患者。判别分析表明，皮肤电无反应和症状是结果的唯一独立预测因素。
