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鸦片酊维持治疗:关于治疗入组相关因素的初步定性研究

Maintenance Treatment with Opium Tincture: A Preliminary Qualitative Study of the Factors Related to Treatment entry.

作者信息

Daneshmand Reza, Alam Mehrjerdi Zahra, Samiee Mercede

机构信息

1. Razi Psychiatric Hospital, University of Social Welfare and Rehabilitation Sciences , Tehran, Iran.

2. Program of International Research and Training, National Drug and Alcohol Research Centre, Faculty of Public Health & Community Medicine, University of New South Wales , Sydney, Australia.

出版信息

Iran J Public Health. 2014 Aug;43(8):1123-31.

Abstract

BACKGROUND

The current preliminary study aimed to explore the reasons that a group of opiate-dependent patients reported for entry into opium tincture treatment (OTT).

METHODS

Through examinations of 52 qualitative focus group interviews with patients from six OTT centers and 10 health providers (in key informant interviews) in Tehran, this study highlights the factors that participants reported as the reasons associated with entry into OTT. Quantitative data including demographic data and details of drug use were analyzed by using SPSS.v.18.0. Qualitative data was analyzed by using Atlas-ti software.

RESULTS

86.5% of patients were male and 13.5% were female. The median age of patients was 39 yr. The most frequently reasons associated with entry into OTT included methadone misconceptions including dissatisfaction with taking methadone as a chemical medication, methadone dependence, and long duration of MMT. The other reasons included the recommendation of other people in treatment and OT-related characteristics and expectations including the herbal compound of OT, treating opiate craving and withdrawal symptoms, and improving general health.

CONCLUSION

The study findings preliminarily showed the reasons associated with entry into OTT in a sample of treatment seekers. Longitudinal studies with more representative samples and follow-up stages are required to evaluate the clinical effectiveness of OTT as a maintenance treatment in comparison with methadone and buprenorphine. Patient-centered program and policy implications are discussed.

摘要

背景

当前的初步研究旨在探究一组阿片类药物依赖患者报名参加鸦片酊治疗(OTT)的原因。

方法

通过对来自德黑兰六个OTT中心的患者进行52次定性焦点小组访谈以及对10名医疗服务提供者进行关键 informant 访谈,本研究突出了参与者所报告的与进入OTT相关的因素。使用SPSS.v.18.0分析包括人口统计学数据和药物使用细节在内的定量数据。使用Atlas-ti软件分析定性数据。

结果

86.5%的患者为男性,13.5%为女性。患者的中位年龄为39岁。与进入OTT相关的最常见原因包括对美沙酮的误解,如对将美沙酮作为化学药物服用不满意、美沙酮依赖以及美沙酮维持治疗时间长。其他原因包括治疗中其他人的推荐以及与OTT相关的特征和期望,如OTT的草药成分、治疗阿片类药物渴望和戒断症状以及改善总体健康状况。

结论

研究结果初步显示了在一组寻求治疗者样本中与进入OTT相关的原因。需要进行具有更具代表性样本和随访阶段的纵向研究,以评估OTT作为维持治疗与美沙酮和丁丙诺啡相比的临床效果。讨论了以患者为中心的项目和政策影响。

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