Dinger Ulrike, Köhling Johanna, Klipsch Ottilia, Ehrenthal Johannes C, Nikendei Christoph, Herzog Wolfgang, Schauenburg Henning
Klinik für Allgemeine Innere Medizin und Psychosomatik, Universitätsklinikum Heidelberg.
Psychother Psychosom Med Psychol. 2015 Jul;65(7):261-7. doi: 10.1055/s-0035-1545306. Epub 2015 Apr 30.
Depressions are frequent disorders in psychosomatic medicine and psychotherapy. However, there are only few controlled studies comparing different levels of care for depressed patients. Especially the efficacy of day-clinic psychotherapy for depression remains understudied. The pilot study aims to close this gap by examining the feasibility of a randomized-controlled trial comparing day-clinic and inpatient psychotherapy for depression in a routine hospital setting. The current paper adds the secondary outcome measures on patient self-reported symptoms and interpersonal problems. In addition, findings of a 6-month follow-up are analyzed. Overall, 44 patients were recruited and randomly allocated to either day clinic or inpatient psychotherapy for 8 weeks. Depressive symptoms and interpersonal problems decreased during treatment, and follow-up scores stayed below intake scores. There were no differences between the treatment groups in this pilot study. For the future, it is desirable to compare randomized patients with those patients who received their preferred treatment option. Although the findings need to be replicated in larger samples, they appear promising for day-clinic psychotherapy. The better understanding of differential effectiveness of different levels of care of patient subgroups remains an important goal.
抑郁症是心身医学和心理治疗中常见的疾病。然而,比较抑郁症患者不同护理水平的对照研究却很少。尤其是日间门诊心理治疗对抑郁症的疗效仍未得到充分研究。这项初步研究旨在通过在常规医院环境中检验一项比较日间门诊和住院心理治疗对抑郁症疗效的随机对照试验的可行性来填补这一空白。本文增加了关于患者自我报告症状和人际问题的次要结局指标。此外,还分析了6个月随访的结果。总体而言,招募了44名患者,并将他们随机分配到日间门诊或住院心理治疗组,为期8周。治疗期间抑郁症状和人际问题有所减轻,随访得分低于初始得分。在这项初步研究中,治疗组之间没有差异。未来,比较随机分组的患者与接受其首选治疗方案的患者是很有必要的。尽管这些发现需要在更大的样本中重复验证,但它们对日间门诊心理治疗似乎很有前景。更好地理解不同护理水平对患者亚组的不同疗效仍然是一个重要目标。