Fiorio R, Bellantuono C, Arreghini E, Leoncini M, Micciolo R
Istituto di Psichiatria, Università di Verona, Italy.
Int Clin Psychopharmacol. 1989 Jan;4(1):7-17. doi: 10.1097/00004850-198901000-00002.
A study on psychotropic drug monitoring was carried out in Verona over a 2-week period using information obtained during consultation with 3 GPs. Psychotropic drugs accounted for 23.4% and 24.3% of all prescriptions in men and women respectively. Benzodiazepines were the most frequently prescribed: 76% and 72% of all psychotropic prescriptions respectively in women and in men. No significant association between psychotropic drug prescription and age, sex, marital status and occupation was found in the present survey. In men only, those patients with higher educational level were more likely to receive a prescription for psychotropic drugs than those with a lower educational level. About 70% of men and 60.4% of women diagnosed by the GP as having a psychiatric problem were prescribed a psychotropic drug. However, the probability of a psychotropic being prescribed, when a psychiatric problem is identified by the GP, was significantly higher (p less than 0.05) in men than in women: odds ratio 39.37 and 16.33 respectively. Psychotropic drugs were prescribed in 35% of men and in about 48% of women in which a social problem was identified by the GP. Women were about 5 times more likely to receive a prescription than men: odds ratio 12 and 2.75 respectively. A significant influence of physical ill-health and educational level on psychotropic prescription emerged: both effects were independent of sex, psychiatric morbidity and social problems. Using a logistic regression analysis, an interactive effect between sex and conspicuous psychiatric morbidity and between sex and social problems was also found.
在维罗纳进行了一项为期两周的精神药物监测研究，使用了与3名全科医生会诊时获得的信息。精神药物分别占男性和女性所有处方的23.4%和24.3%。苯二氮䓬类药物是最常被处方的：在女性和男性中，分别占所有精神药物处方的76%和72%。在本次调查中，未发现精神药物处方与年龄、性别、婚姻状况和职业之间存在显著关联。仅在男性中，教育水平较高的患者比教育水平较低的患者更有可能接受精神药物处方。被全科医生诊断患有精神问题的男性中约70%和女性中约60.4%被开了精神药物。然而，当全科医生确定存在精神问题时，男性被开精神药物的概率显著高于女性（p小于0.05）：优势比分别为39.37和16.33。在被全科医生确定存在社会问题的男性中，35%被开了精神药物，女性中约48%被开了精神药物。女性接受处方的可能性约为男性的5倍：优势比分别为12和2.75。身体不健康和教育水平对精神药物处方有显著影响：这两种影响均独立于性别、精神疾病发病率和社会问题。使用逻辑回归分析，还发现了性别与明显精神疾病发病率之间以及性别与社会问题之间的交互作用。
